Vemlidy vs Viread for hepatitis B – Differences and side effects

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Vemlidy vs Viread for hepatitis B - Differences and side effects

Vemlidy

It is the brand name of a drug called tenofovir alafenamide, which belongs to a group of drugs known as nucleoside analog reverse transcriptase inhibitors.

Mechanism of action

It works by stopping the replication of the virus.

Applications

This prescription medication is used to treat chronic hepatitis B virus (HBV) in combination with other antiviral drugs in adults with stable liver disease (compensated).

Dosage

The usual recommended dose is 25 mg (one tablet) taken orally once a day with food.

Side effects and precautions

Common side effects may include:

feeling tired; Diarrhea; Back pain; dizziness; depressed mood; barf; cough headaches; nausea; sleep problems (insomnia); stomach ache; itching or rash; fever; changes in the shape or location of body fat; weakness.

Rare side effects It can include ::

feeling short of breath; easy bruising or unusual bleeding; wheezing Flu symptoms; a dry cough a sore throat sores in your genital or anal area; problems with balance or movement of the eyes; swelling of your feet or ankles; Chest pain; weakness or prickly sensation; painful or difficult urination; feel anxious or irritable; little or no urination; high cardiac rhythm; loss of interest in sex; jaundice (yellowing of the skin or eyes); weightloss; impotence; menstrual changes; loss of control of the bladder or bowel; swelling in your neck or throat; severe lower back pain; clay-colored stools; unusual tiredness

Contraindications

To make sure this medication is safe for you, tell your health care provider if you have:

low bone mineral density; kidney disease; liver disease.

Alcoholalcohol

Avoid drinking alcoholic beverages while taking this medication, since alcohol consumption can substantially increase the risk of serious side effects.

Drug interactionsdrug pills

You can interact negatively with other medicationsespecially

emtricitabine; abacavir Kaletra (lopinavir / ritonavir); Acetylsalicylic acid (aspirin); lamivudine; adefovir; Paracetamol (paracetamol); Aspir 81 (aspirin); Reyataz (atazanavir); atazanavir; Valproate sodium (valproic acid); Chlorpheniramine; Wellbutrin XL (bupropion); didanosine; zidovudine; L-arginine (arginine); ER tramadol hydrochloride (tramadol); Phenytoin sodium (phenytoin).

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Pregnancy and lactation

If you are pregnant, your name may appear in a pregnancy registry to assess any effect of tenofovir on the developing fetus.

Do not breast-feed while you are taking this medicine, as it may pass into breast milk and harm a nursing baby.

Viread

It is the brand name of a drug called tenofovir disoproxil fumarate, which belongs to the family of drugs known as nucleoside analog reverse transcriptase inhibitors.

Mechanism of action

This medication works by preventing the virus from replicating.

Applications

This prescription medication is used along with other medications to treat human immunodeficiency virus and chronic hepatitis B infections.

Dosage

The usual recommended dose is a tablet that is taken orally once a day with food.

Side effects and precautions

Common side effects may include:

Back pain; Diarrhea; headaches changes in the shape or location of body fat; vomiting feeling tired; dizziness; nausea; weakness; depressed mood; stomach ache; sleep problems (insomnia); cough; itching or rash; fever.

Rare side effects may include:

feeling short of breath; easy bruising or unusual bleeding; unusual tiredness wheezing flu symptoms; clay-colored stools; a dry cough a sore throat severe pain in the lower back; sores in your genital or anal area; swelling in your neck or throat; problems with balance or movement of the eyes; swelling of your feet or ankles; loss of control of the bladder or bowel; Chest pain; weakness or prickly sensation; painful or difficult urination; feel anxious or irritable; menstrual changes; little or no urination; high cardiac rhythm; loss of interest in sex; jaundice (yellowing of the skin or eyes); impotence; weightloss.

Contraindications

To make sure that this nucleoside reverse transcriptase inhibitor is safe for you, tell your healthcare provider if you have:

low bone mineral density; kidney disease; liver disease.

Alcohol

Avoid drinking alcoholic beverages while taking this medication, since alcohol consumption can substantially increase the risk of serious side effects.

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Drug interactions

You may interact negatively with other medications, especially:

Cymbalta (duloxetine); acyclovir; Isentress (raltegravir); aspirin; lisinopril; Baraclude (entecavir); Norvir (ritonavir); clonazepam; Prezista (darunavir); Emtriva (emtricitabine); tramadol; Epivir (lamivudine); Truvada (emtricitabine / tenofovir); gabapentin; Ziagen (abacavir); ibuprofen; sovaldi; trazodone; Kaletra (lopinavir / ritonavir); Reyataz (atazanavir); levothyroxine; Omeprazole; Zepatier; metformin.

Pregnancy and lactation

Do not breast-feed while you are taking this medicine, as it may pass into breast milk and harm a nursing baby.

If you are pregnant, your name may appear in a pregnancy registry to assess any effect of tenofovir on the developing fetus.

In a nutshell – Vemlidy vs Viread

Vemlidy (active ingredient – tenofovir alafenamide) is an antiviral medication that is used to treat chronic hepatitis B and HIV (the virus that can cause acquired immune deficiency syndrome). It works by preventing the hepatitis B virus or the human immunodeficiency virus from multiplying in the body.

Viread (active ingredient – tenofovir disoproxil fumarate) is an antiviral medication that is used to treat chronic hepatitis B and HIV (the virus that can cause acquired immune deficiency syndrome). It works by preventing the hepatitis B virus or the human immunodeficiency virus from multiplying in the body.

In conclusion, both drugs are generally well tolerated and the rates of adverse events are around 1 percent. However, according to the studies, Vemlidy has a greater plasma stability compared to Viread, therefore, it can be administered at a lower dose, which produces less tenofovir in the bloodstream.

In addition, Vemlidy has been shown to have an antiviral effectiveness similar to that of Viread, but it has improved the safety of bones and kidneys.

Regarding its price, the average retail price of 30 tablets of Vemlidy 25 mg is $ 1,090, while the average retail price of 30 tablets of Viread 300 mg is $ 310.

Referenceshttp://www.ema.europa.eu/docs/en_GB/document_library/EPAR_-_Phttp://www.who.int/selection_medicines/committees/expert/21/

Vemlidy vs Viread for hepatitis B – Differences and side effects, Source: https://www.yourhealthremedy.com/health-tips/vemlidy-vs-viread/

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