Tedizolid vs Linezolid – Uses, side effects, differences

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Tedizolid vs Linezolid - Uses, side effects, differences

Tedizolid

It is a medicine (brand name – Sivextro) that belongs to a class of medications called oxazolidinone antibiotics. This medication is used to treat serious bacterial infections of the skin and acts by killing the bacteria or preventing their growth.

It was approved for the first time by the Food and Drug Administration of the United States in 2014.

Applications

It is usually prescribed to adults for treatment of acute bacterial infections of the skin (ABSSSI) caused by susceptible isolates of a few gram-positive bacteria.

Acute bacterial infections of the skin and the structure of the skin (such as major skin abscesses, erysipelas or cellulitis, and wound infections) can be life-threatening and may require hospitalization.

Note – It will not work for the flu, colds and other viral infections.

Dosage

the usual recommended dose 200 mg is administered once a day for six days orally or as an intravenous infusion in people older than 18 years.

Side effects and precautions

Common side effects It can include:

Headaches Diarrhea; dizziness; barf nausea.

Rare side effects may include:

pain behind your eyes; severe stomach pain; Eye sight problems; numbness in the hands or feet; diarrhea that is watery.

before taking this medication, tell your health professional:

If you have any medical conditions; if you are allergic to similar medications; if you are going to have surgery, including dental surgery; if you are breastfeeding; if you are pregnant or plan to become pregnant; if you are taking herbal products, nutritional supplements and vitamins; If you are taking other prescription medications and without a prescription.

Because he can cause dizzinessDo not operate or drive heavy machinery until you know exactly how this medicine affects you.

Linezolid

Is a drug (brand name – Zyvox) that belongs to the family of medications called antibiotics. It is used to treat pneumonia, skin infections and blood infections. This antibiotic works by preventing bacteria from producing proteins, which inhibits bacterial growth.

It is on the WHO list of essential medicines. It was discovered in the mid-1990s and was first approved for commercial use in 2000.

Applications

It is usually used to kill certain types of bacteria that cause infections in the lungs, abdomen, skin, urinary tract, and the structure of the skin.

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It is available for oral and intravenous administration and its activity is focused on gram-positive bacteria, such as: vancomycin-resistant enterococci, methicillin-resistant Staphylococcus aureus and penicillin-resistant Streptococcus pneumoniae.

Dosage

For children under 12 years of age, the usual recommended dose is based on body weight and should be determined by a health professional. It is usually 10 mg per kilogram of body weight every 8 or 12 hours.

For adults and children over 12 years of age, the usual recommended dose is 400 or 600 mg every 12 hours.

Side effects and precautions

Common side effects may include:

yeast infection in the mouth; itching or vaginal discharge; constipation; headaches vomiting dizziness; nausea; problems sleeping; unusual or unpleasant taste in the mouth; Discolored tongue.

Rare side effects may include:

Feel nervous sores in the mouth and throat; perspiration; body pain; fast heart rate; fever; irritability; feeling dizzy or short of breath; Confusion; problems to see the color; weakness; bruising easily; unusual hunger; seizures diarrhea that is watery a tingling sensation in the hands or feet; blurry vision; problems to concentrate; high heart rate.

Before taking this antibiotic, tell your healthcare provider if you have or have had:

a tumor of the adrenal gland; an infection that lasts a long time; allergies to any medication; Diabetes mellitus type 2; liver disease; if you are breast-feeding a baby; if you are pregnant or plan to have a baby; kidney disease; seizures immune system problems; an overactive thyroid (hyperthyroidism); high blood pressure; a condition in which a tumor secretes serotonin (carcinoid syndrome).

Note: While you are taking this antibiotic, try to avoid eating mature cheese, yeast extracts, sauerkraut, bean pods, beans, papaya products, turkey, avocados, preserved figs, salami, salami, chicken liver, pickled herring, sour cream, bananas, raisins, yogurt and soy bean products (such as soy sauce), as well as drinking beer and red wines. These foods interact with this antibiotic and can cause more side effects.

Tedizolid vs Linezolid – Which is better for bacterial skin infections?

Linezolid is an antibiotic that is used to treat infections of the skin, lungs, and blood. It is used under conditions of vancomycin resistance. It was the first oxazolidinone approved for the treatment of infections caused by gram-positive pathogens, including methicillin-resistant Staphylococcus aureus.

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Tedizolid is a new antibacterial prodrug with a very effective activity against gram-positive pathogens, such as Streptococcus pyogenes, S. aureus susceptible to methicillin, Streptococcus agalactiae, coagulase-negative staphylococci and enterococci.

However, in 2014, the United States Food and Drug Administration approved tedizolid phosphate (brand name – Sivextro) as a second generation oxazolidinone with a potential potency of 4 to 16 times against MRSA compared with linezolid.

In addition, gastrointestinal adverse events (such as abdominal pain, severe constipation, and acid reflux) were less frequent with tedizolid (Sivextro) than with linezolid (Zyvox).

5 Natural antibiotics That fights the infection

# 1 oregano oil

Oregano oil is produced through the steam distillation of fresh leaves of oregano, a perennial plant belonging to the Labiatae botanical family.

Oregano oil can be a effective treatment against drug-resistant bacteria, according to a study conducted in 2001 at the Georgetown University Medical Center. Experts say it may be due to its content of two potent compounds: thymol and carvacrol.

# two Garlic

It is said to be one of the most effective natural antibiotics. It is also one of the oldest natural remedies for many conditions. In fact, the use of garlic as a natural healing remedy dates back more than 7,000 years.

The sulfur compound in garlic, called allicin, acts like a natural antibiotic, according to a 1999 study published in the journal Microbes and Infection.

Onion # 3

It is closely related to garlic and has similar beneficial properties (it also contains allicin), such as: preventing flu and colds, fighting bacterial infections, as well as reducing inflammation and pain.

# 4 Gold seal

Berberine, an alkaloid found in this perennial herb, acts against gram-positive bacteria, including methicillin-resistant Staphylococcus aureus.

# 5 coconut oil

It contains lauric acid, a compound that possesses antiviral, antimicrobial and natural antifungal attributes. Coconut oil can be used for infections of yeast, candida, inflammation, cough and warts.

Referenceshttp://www.nejm.org/doi/full/10.1056/NEJMc1500286#t=articlehttps://www.ncbi.nlm.nih.gov/pubmed/24909499https://www.ncbi.nlm.nih.gov/pubmed/24238896https://academic.oup.com/cid/article/58/suppl_1/S51/508285

Tedizolid vs Linezolid – Uses, side effects, differences, Source: https://www.yourhealthremedy.com/health-tips/tedizolid-vs-linezolid/

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