Side effects of hyaluronic acid: liver, skin care and cancer

Filed in: Health Tips.

Side effects of hyaluronic acid: liver, skin care and cancer

Hyaluronic acid (HA), also called hyaluronan or sodium hyaluronate, is a natural glycosaminoglycan that occurs naturally in the connective tissues and structure of the skin.

It is composed of identical molecules of 2-acetamido-2-deoxy-d-glucose and d-glucuronic acid and alternating in the heteropolysaccharide.

The average individual has approximately 15 grams of HA in their body with 1/3 of which is synthesized and degraded daily.

Meyer and Palmer discovered HA in 1934 and was used as a substitute for egg white in bakery products. In the laboratory, it is made by bacteria or extracted from combs of rooster. Therefore, some HA supplements are plant-based and others are not.


It is usually used in anti-aging products that can be applied topically on the skin or as a pill or injection for joint disorders such as osteoarthritis. In addition, it is used during some eye surgeries and as lip filling in plastic surgery.

Side effects of oral hyaluronic acid supplements or injections

Note – the supplement The HA form is considered safe for most people. However, excessive use (or injections) can lead to some side effects.

Also, it is not recommended to drink alcoholic beverages while taking this supplement, as alcohol may increase the risk of side effects of HA.

Side effects of HA include gastrointestinal discomfort, headaches, ulceration, drowsiness, pain in the joints, loss of appetite.

The pregnancyGood for pregnant women

Pregnant and lactating women should not take this supplement, as it appears that this acid can enter breast milk and may adversely affect a developing baby.

In addition, it interacts with certain non-steroidal anti-inflammatory drugs.


After using a cream with HA, some people may experience a slight redness or extreme itching.

In addition, after an injection with HA, some experience pain at the injection site and itching.


HA can promote the spread and growth of cancer cells and should not be used by cancer patients because when a cancer cell with this CD44 protein tries to spread and grow, this supplement helps it to do so.

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In addition, according to a study conducted in 1996 in the Department of Anatomy and Cell Biology, Boston, USA. UU., HA increases the attachment to ovarian and breast cancer.


Like any other prescription medicine, supplements have chemicals that, once absorbed, are processed by the liver.

The belief is that supplements are harmless because they are natural compounds and do not harm, so the connection is never on the table.

In addition, dietary supplements are not inspected by the US Food and Drug Administration. UU In the same measure as prescription medications.

Benefits of health

In short, HA has powerful anti-aging functions and is one of the best moisturizing substances for skin or skin prone to peeling.

Good for dry skinSKIN

The moisture binding property of this acid is beneficial and important when it comes to the aging process of the skin. It is considered a glycosaminoglycan (it has the capacity to contain a large volume of water) and 1 gram of HA can contain up to 6 liters of water.

However, due to its large size (compared to other acids), it is more difficult for skin care manufacturers to produce a product with HA that can penetrate the skin.

Sun tanningsunbathing

When the skin is exposed to excessive ultraviolet rays, it becomes inflamed and the cells of the dermis stop producing HA, which can cause an increase in the speed of its degradation.

Therefore, the longer you are exposed to ultraviolet rays, the worse the damage to the skin will be. A cream containing HA can stimulate the production of collagen in the skin and increase the level of hydration.

Synovial fluidIF NOT

Synovial fluid removes debris from the cartilage, functions as a buffer that lubricates the fluid in the joint tissues and supplies nutrients to the cartilage.

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HA is secreted in the synovial fluid, making the fluid viscous. However, as we age, the viscosity of the joint fluid decreases and may cause joint problems. You can take 50 milligrams of HA orally once or twice a day with meals.

Gum diseasemodel

Gum disease is an inflammation of the gums caused by bacteria on the plaque. Gum disease can occur at any age, but it is more common among adults. Flossing and brushing regularly can help remove the plaque.

HA is an essential component of the connective tissue in the gums and reduces any inflammation that causes bleeding from the gums, in addition to helping the regeneration of new tissue from the gums.


It is found in the vitreous fluid (the transparent gel found between the lens and the retina of the eyeball) in the eyes and gives them their characteristics and shape.

In addition, during eye procedures, it is injected directly into the eye to help replace natural fluids lost during eye surgery.

Wrinkle reductionskin

The skin begins to lose HA from 18 years, but the damage of the skin by the loss of HA (such as wrinkles) usually does not appear until the early 40's.

Therefore, by reducing wrinkles, HA increases the tone of the skin and makes the skin look smooth and smooth.

Foods rich in hyaluronic acid

Foods such as green leafy vegetables, soy products and root vegetables contain this acid. More importantly, a diet rich in potatoes and sweet potatoes increases the amount your body produces on its own.

As well, eat food High content of resveratrol, zinc and magnesium Which also increases HA production. Finally, consuming a lot of water creates the right conditions for HA to hydrate the skin and other cellular tissues.


Side effects of hyaluronic acid: liver, skin care and cancer, Source:

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