Pantoprazole vs Omeprazole – What is the best treatment for gastric ulcer?

Filed in: Health Tips.

Pantoprazole vs Omeprazole - What is better to treat gastric ulcer?

Pantoprazole

It belongs to the group of drugs called proton pump inhibitors that block the proton pump in the gastric parietal cells, which reduces the general secretion of gastric acid.

This medication may be used to treat gastroesophageal reflux disease (GERD), a serious condition in which the backward flow of stomach acid leads to injury to the esophagus. Gastroesophageal reflux disease is a chronic and recurrent disease that, according to the CDC, affects more than 19 million people in the United States.

It is also used to treat Zollinger-Ellison syndrome (characterized by gastrin-secreting tumors), as well as in the treatment of peptic ulcers (sores in the lining of the duodenum or stomach).

Dosage

Children can take this medication between 20 and 40 mg per day, depending on the severity of their symptoms and their size. Adults commonly use a 40 mg tablet per day for up to two months. If the symptoms of gastroesophageal reflux disease continue Beyond this point, contact your health care provider to determine the best course of action.

Swallow the entire tablet with a glass of water. Do not chew or crush this medication, as it does not work properly if the tablet is chewed or crushed.

Applications

It is used to treat Zollinger-Ellison syndrome, a rare condition in which the stomach produces large amounts of acid, considerably more than in reflux disease and ulcers.

This medication can also be used to prevent ulcers caused by medications, such as nonsteroidal anti-inflammatory drugs (ibuprofen, diclofenac, or naproxen).

When combined with antibacterial agents in the eradication of the bacterium Helicobacter pylori, this drug is well tolerated and, in addition, offers the potential advantage of a minimal risk of drug interaction.

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Side effects Y Precautions

Side effects can include:

unexplained weight loss; increase in hunger; perspiration; nausea; increased urination; increased thirst; difficulty breathing; bad breath; reddened skin; abdominal pain.

In high doses and in long-term users (especially people over 50), this medication may increase the possibility of bone fracture in the wrist, hip or spine. In addition, long-term treatment with this medication can make it harder for the human body to absorb much-needed vitamin B12.

There are no conclusive studies on the use of this drug in pregnant or lactating women, therefore, stay safe and do not use this medicine without the approval of your doctor.

Omeprazole

It belongs to a class of drugs with the scientific name of the proton pump inhibitors that work by blocking the production of acid in the stomach. This medication is commonly used to treat gastroesophageal reflux disease (GERD), gastric and duodenal ulcers, and Zollinger-Ellison syndrome (occurring in only 1 in 1 million people).

It is available in brand and generic versions and without a prescription.

Applications

It is used with other medications or just to treat a condition in which the backward flow of stomach acid causes a lesion of the esophagus and heartburn, called GERD (gastroesophageal reflux disease).

This medication may also be given (along with antibiotics) to kill H. pylori, a harmful bacteria found in the stomach that can cause ulcers. The optimal dose for therapy with anti-Helicobacter pylori bacteria is 40 mg per day (in 1 or 2 divided doses) for 7, 10 or 14 days in combination with two antibacterial agents.

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In addition, it can help in the healing process where the damage has already occurred, as well as prevent the formation of ulcers.

Side effects and precautions

Common side effects include:

nausea; vomiting gas; fever; flatulence; abdominal pain; constipation; Diarrhea; headache.

It is recommended to stop breastfeeding while using this medication, as harmful effects have been shown in babies in recent studies with women who are breastfeeding a baby.

Like other proton pump inhibitors, long-term use can cause low levels of magnesium in the blood (symptoms include nausea, loss of appetite, drowsiness, vomiting, personality changes, weakness, tremors and muscle spasms) .

It can also cause weak or broken bones because this drug causes a decrease in the production of stomach acid and the human body needs stomach acid to absorb the calcium from the food.

More importantly, it can cause systemic lupus erythematosus and cutaneous lupus erythematosus, autoimmune diseases that generally affect young and middle-aged adult women. This medicine may also increase the incidence of Clostridium difficile, a serious intestinal infection.

Prolonged exposure of the liver to this medication can cause damage to the liver cells and cause inflammation of the liver.

Pantoprazole vs Omeprazole – What is the best treatment for gastric ulcer?

Both drugs are proton pump inhibitors that work by blocking the production of stomach acid. Studies that compared these two proton pump inhibitors in patients with acute duodenal ulcers found them equally effective and safe.

Pantoprazole vs Omeprazole: What is the best treatment for gastric ulcer? Source: https://www.yourhealthremedy.com/health-tips/pantoprazole-vs-omeprazole/

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