Orotato Magnesium – Side Effects And Benefits (Sleep And Anxiety)

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Orotato Magnesium - Side Effects And Benefits (Sleep And Anxiety)

Magnesium orotate (MO) is a form of magnesium supplement That consists of magnesium and orotic acid.

Orotic acid, formerly known as vitamin B13 and initially considered part of the B vitamins, is actually a compound made in the body (therefore, it is not a vitamin) and is used to improve endurance and performance athletic, as well as for the health of the heart.

MO is different from regular magnesium and performs similar tasks in the human body as magnesium The carbonate, however, is easily absorbed in the tissues.

Magnesium Orotate vs. Magnesium Citrate

Magnesium Citrate is a preparation of Mg in the form of salt with citric acid in a ratio of 1: 1. However, this type of Mg supplement retains water in the intestines by osmosis. This commonly produces a bowel movement within 30 minutes to six hours.


Mg is a cofactor in more than 300 enzyme systems that regulate a variety of biochemical reactions within the human body, such as muscles and nerves. function, blood pressure, protein synthesis and blood sugar activity. It is also required for the conversion of vitamin D (also known as the sun's vitamin) into its active form.

Prevents Hypomagnesemia

Some people use this supplement to prevent or treat Mg deficiency, while others use it for their orotic acid (it helps Mg pass through cell membranes).

Common symptoms of a Mg deficiency can include:

muscle contractions or cramps; problems in the teeth; irritability; migraines; hardening of the arteries (arteriosclerosis); hypertension; accelerated heart rate or palpitations; unpleasant body odor; Premenstrual syndrome and menstrual cramps; contractions in the eyes; autism; constipation; difficulty swallowing; insomnia; headaches sensitivity to loud noises; osteoporosis; anxiety; ADD; chronic fatigue; fibromyalgia; diabetes; obesity; asthma; irritable Intestinal syndrome; kidney stones

It is estimated that only 32 percent of the adult population in the United States achieves the recommended daily intake of Mg.

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Mg deficiency Causes can include:

autoimmune disorders; Elevated inflammatory cytokines; high consumption of alcoholic beverages; long-term use of Proton-pump inhibitor, like – Prevacid (lansoprazole) and Prilosec (omeprazole); The use of diuretics, such as – Lasix (furosemide) and Hydrodiuril (hydrochlorothiazide) may increase the loss of Mg in the urine; Digestive diseases can also lead to this deficiency, since problems with the gastrointestinal tract can cause the body not to absorb minerals and vitamins correctly, leading to deficiencies.


The disorders related to anxiety are the most frequent affective affections present in the general population. Anxiety is described as nervousness or fear of what might happen.

Currently, more than 40 million people in the US UU Over 18 years suffer from this condition, according to the Anxiety and Depression Association of America.

The good news is that clinical research He concluded that this essential mineral can be useful as a treatment to reduce anxiety levels.

For example, a French study established that people suffering from generalized anxiety disorder (GAD) experienced a considerable improvement in their anxiety symptoms by following an Mg regimen.


10 to 15 percent of American adults have problems Sleeping all the time In addition, 30 to 40 percent of adults say they have occasional insomnia, according to the National Sleep Foundation.

Mg plays a crucial role in sleep because it induces sleep states before falling asleep. In addition, this mineral regulates melatonin, a hormone secreted by the pineal gland in the brain that guides the cycles of sleep and wakefulness in the human body.

This mineral is also important for the function of GABA receptors (a class of receptors that respond to the neurotransmitter gamma-aminobutyric acid), which exists in all areas of the nervous system and the brain.

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GABA is a neurotransmitter that the brain necessarily to turn off. Without it, you can lie down in bed without falling asleep.


Heavy metals such as aluminum, lead and mercury are strongly associated with anxiety and other neurological disorders (such as Parkinson's disease).

Maintaining high levels of Mg can prevent deficiencies that reduce the functional capacity of the body to detoxify heavy metals and cause breakdowns in detoxification systems.

Bone health

Mg plays an important role in balancing calcium levels in the body. Interestingly, many people are aware of the fact that bone health and calcium go hand in hand.

However, what people do not realize is that without sufficient Mg intake, calcium levels are unbalanced.

Rise the levels of energy

According to a study conducted by the USDA, people with low levels of Mg in the muscles spend more energy during physical exercise, therefore, they tire easily.


The daily reference intake value for Mg is 265 mg for non-pregnant women, non-infants over 30 years and 350 mg for men over 30 years.

Side effects of magnesium orotate

Too much Mg (from supplements) can cause diarrhea, low blood pressure, loose stools, irregular heartbeat, confusion, rash, breathing problems, upset stomach, and dizziness.

If you have kidney or heart disease, do not take any type of Mg supplement without first checking with your health care provider.

Most importantly, if you are taking calcium channel blockers for high blood pressure, talk to your healthcare professional, as it may increase the possibility of adverse effects of these medications.


Magnesium Orotate: side effects and benefits (sleep and anxiety), source: https://www.yourhealthremedy.com/health-tips/magnesium-orotate/

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