Kerydin vs Jublia – Which is better to treat onychomycosis?

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Kerydin vs Jublia - What is better to treat onychomycosis?

Kerydin

It is the brand name of a generic drug called tavaborole, which belongs to a group of drugs known as antifungals.

The drug acts by inhibiting an enzyme known as cytosolic leucyl transfer RNA synthetase, which plays an essential role in the synthesis of essential fungal proteins. This leads to the death of the fungus.

It is produced by Anacor Pharmaceuticals, a company focused on the development of new small molecule therapies. The US Food and Drug Administration UU Originally approved this medication in 2014.

Applications

This prescription medication is indicated for onychomycosis of the toenails due to Trichophyton mentagrophytes or Trichophyton rubrum. It is the first topical antifungal oxaborol class that can be used for onychomycosis.

Image credit: https://commons.wikimedia.org/wiki/File:Onychomycosis_due_to_Trychophyton_rubrum,_right_and_left_great_toe_PHIL_579_lores.jpg

Onychomycosis is a fungal infection that affects the nails of the feet or nails. It is the most common nail disease and constitutes approximately fifty percent of all nail abnormalities. According to statistics, about 10% of the adult population in the United States is affected.

The symptoms

You can have this condition If one or more of your nails are:

that smells slightly disgusting; a dark color, caused by debris that accumulates under the nail; distorted in form; brittle, crumbly or unequal; whitish to yellow-brown coloration; thickened

Risk factor's

Factors that may increase your risk of developing onychomycosis include:

have a weakened immune system; reduced blood flow; have diabetes mellitus type 2; have a small injury to the nail or skin; walk barefoot in humid communal areas, such as gyms, swimming pools and showers; have a history of athlete's foot (tub pedis); sweating a lot to be 65 or older.

Dosage

The medication is applied topically on the affected toenail once a day. Continue to use the medication for the entire prescribed time, even if the infection seems to have disappeared.

Notes – If your symptoms do not improve, call your healthcare provider. Before putting this antifungal, clean the nails and dry well. Avoid trying to put the medicine on the skin around the treated nail.

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If you have accidentally applied the antifungal on the skin around the nail and other areas of the body, you can wash them with soap and water. Wash your hands with soap and water after applying this medication.

Side effects and precautions

Side effects may include:

redness, itching and swelling; ingrown toenail; skin peeling

Pregnancy and lactationh

It is not known with precision if this antifungal is excreted in breast milk after topical application. Tell your doctor that you are breast-feeding a baby before using this medicine.

There are no well-conducted clinical studies to determine the safe use of this antifungal by pregnant women. Tell your doctor that you are pregnant before using this medicine.

Jublia

It is the brand name of a medicine called efinaconazole that belongs to the class of medications called antifungal agents. It works by blocking the production of a compound known as ergosterol, which is found in the cell walls of fungi.

The drug is produced by Valeant Pharmaceuticals, a specialized multinational pharmaceutical company based in Laval, Canada. It was originally approved by the FDA of the United States in June 2014.

Applications

This prescription medication is usually used to treat onychomycosis, a fungal infection of the toenails.

Image credit: https://commons.wikimedia.org/wiki/File:Onychomycosis.JPG

Note: The safety and efficacy of this medication in children have not been established, therefore it may not be safe to apply this medication to children's nails.

Dosage

Apply this antifungal to the affected nails once a day for 48 weeks (approximately 11 months), using the integrated flow brush applicator.

Note: This antifungal is only for topical use and should not be applied to any other area of ​​the body nor should it be taken orally. Do not use cosmetic products for your nails or nail polish while using this medication.

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Side effects and precautions

Common side effects It can include:

ingrown toenail; Itch; Pain or irritation where this antifungal was applied.

Rare side effects It can include:

severe itching, redness or swelling of the affected nail

Drug interactions

There are no known or significant interactions for this medication.

Pregnancy and lactation

It is not known exactly if this topical antifungal agent passes into breast milk or if it could adversely affect a baby. Count your health care provider If you are breast-feeding a baby.

Also, it is not known if this medicine will harm the unborn baby. Count your health care Professional if you are pregnant or plan to become pregnant while using this topical antifungal.

Conclusion: Kerydin vs. Jublia: effectiveness and costs

Kerydin (active ingredient – tavaborol) is an antifungal that is used to try nail onychomycosis by Trichophyton mentagrophytes or Trichophyton rubrum. The average price of this topical antifungal is around $ 1,500.

In two clinical trials, fungal infection was eliminated with this medication in 6.5 percent of the cases, compared to 0.5 percent using the vehicle alone, and 27.5 percent versus 14 percent. , 6 percent who use the vehicle alone.

Jublia (active ingredient – efinaconazole) is an antifungal medication that is used to treat onychomycosis, a fungal infection of the nail. It is applied on, around and under the nail to reach the site of infection. The average price for the most common version of this antifungal is around $ 575.

In one study, a complete cure was achieved in 17.8% of patients after 48 weeks of efinaconazole application. In the other study, 15.2% of users achieved a cure after 48 weeks.

In conclusion, Kerydin is more efficient in the treatment of onychomycosis but also substantially more expensive.

Referenceshttps://www.jubliarx.com/efficacy-side-effectshttps://www.sciencedirect.com/science/article/pii/S0190962215015121https://www.kerydin.com/Using-Kerydin.aspx

Kerydin vs. Jublia – Which is better to treat onychomycosis?, Source: https://www.yourhealthremedy.com/health-tips/kerydin-vs-jublia/

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