Trazodone is the generic name of a brand name drug called Oleptro. It belongs to the class of medications called antidepressants. The Food and Drug Administration of the United States originally approved it in 1982.
This medication works by affecting the activity of specific neurotransmitters called histamine and serotonin. By increasing the action of serotonin and histamine, this medication increases the total duration of your sleep and helps you fall asleep faster, in addition to reducing the symptoms of depression.
It is used to treat depression, a common and debilitating mood disorder. Depression is more than just sadness in response to the setbacks and struggles of life, this condition changes the way you feel, think and function in regular activities.
It is estimated that 9% of people reported current major or minor depression, according to the Centers for Disease Control and Prevention. The symptoms of a depressive episode may include:
feelings of worthlessness, guilt, impotence; irritability, restlessness; anxious, sad or "empty" mood; persistent physical symptoms that do not respond to treatment, such as: digestive disorders, headaches and pain for which no other cause can be identified; feelings of pessimism, hopelessness; suicide attempts; thoughts of suicide or death; Eat in excess and gain weight or little appetite and weight loss; wake up early in the morning, insomnia (sleep problems) or fall asleep; difficulty remembering, concentrating, making decisions; feeling "slowed down", increased fatigue; low energy levels; Loss of interest or pleasure in activities and hobbies.
Cause of Depression
Doctors are not completely sure what causes depression, but one of the main theories states that depression is caused by an imbalance of some neurotransmitters: natural substances in the spinal cord and brain.
Alcohol and drug use can make depression worse, and treatment is more likely to be successful if alcohol and drugs are avoided. In addition, vitamin D deficiency (also known as solar vitamin) has been recognized as a cause of seasonal affective disorder. In addition, long-term emotional stress (such as constant work stress, abusive relationships and prolonged isolation) can cause depression over time.
This medication is also used to control abnormal and uncontrollable movements that can be experienced as side effects of other medications. In addition, it is used to treat schizophrenia (a mental illness that causes loss of interest in life, unusual or disturbed thoughts and inappropriate emotions), anxiety (excessive worry) and insomnia.
To treat depression, the usual recommended starting dose is 75 mg per day. Your healthcare professional can increase the dose to 300 mg per day depending on your condition.
To treat anxiety, the usual recommended starting dose is 75 mg per day. Your healthcare professional can increase this dose to 300 mg per day.
Notes: It may take up to a month before the full beneficial effects of this medication can be seen. Children under the age of 18 should not take this medication because, in short-term studies in adolescents and children with depression and other psychiatric disorders, antidepressants increased the risk of behavior and suicidal thinking.
Side effects and precautions
Common side effects It can include:
Muscle pain; Headaches; blurry vision; stomach ache; dry eyes; loss of appetite; dry mouth; Confusion; vomiting ringing in the ears; nausea; eruption; diarrhea or constipation; perspiration; erectile dysfunction in men; loss of interest in sex; fatigue; nervousness; tingling sensations; loss of balance
Rare side effects It can include:
swelling of the lips, face or tongue; worsening of depression; panic attacks; irregular heartbeats; suicidal thoughts; seizure; urticaria; a severe rash Chest pain; unusual bleeding or bruising; Fainting; a painful erection that will not go away; difficult breathing
To make sure that this medication It is safe for you, tell your health care provider if you have:
heart disease; kidney disease; liver disease; Narrow-angle glaucoma; seizures or epilepsy; a bleeding or blood clotting disorder; a history of long QT syndrome; He had a heart attack; a story of suicidal thoughts; a history of drug abuse; Bipolar disorder (manic depression).
This medicine belongs to category C, which means that in animal studies, pregnant animals were given this medicine and had some babies who were born with some health problems. Therefore, if you are pregnant or plan to become pregnant, avoid this medication. Also, this medicine is secreted in breast milk and can harm your baby. Therefore, do not use this medication if you are breast-feeding a baby.
Avoid alcohol When taking this medication, as it causes dizziness and drowsiness, as well as will increase the possibility of side effects.
Symptoms of overdose may include vomiting, extreme drowsiness, fast or pounding heartbeat, penile erection that is prolonged or painful, breathing that stops or decreases, or seizures (fainting or seizures).
Important note: An overdose of this medication can be fatal when combined with alcohol, sedatives (diazepam) or barbiturates (phenobarbital).
Discharge and abuse
Currently, there is no record of reported cases of euphoria after taking this medication.
This medication may interact negatively with many different medications, including:
used drugs to treat HIV / AIDS, such as – nelfinavir (Viracept), indinavir (Crixivan) and atazanavir (Reyataz); diuretics; anticoagulants, such as: aspirin, warfarin (Coumadin) and ibuprofen; antibiotics, such as erythromycin (erythrocin) and clarithromycin (biaxin); Selective serotonin reuptake inhibitors, including – fluvoxamine (Luvox) or fluoxetine (Sarafem, Prozac); medicines used to treat mental illnesses, such as – thioridazine; medicines for seizures, such as – phenytoin (Dilantin), phenobarbital (Solfoton, Luminal), ethosuximide (Zarontin), carbamazepine (Tegretol); medications for the heart, such as – verapamil (Isoptin, Calan, Verelan) or sotalol (Betapace); medications used to treat heartburn, such as cisapride (Propulsid) and cimetidine (Tagamet); medications used to treat fungal diseases, including – itraconazole (Sporanox) or ketoconazole (Nizoral); medicines for coughs, colds, and allergies, such as dexamethasone (Decadron).
Also, do not use this medication if you have taken an MAO inhibitor (including – isocarboxazid, phenelzine, linezolid, selegiline, rasagiline, and tranylcypromine) in the last 2 weeks, as a potentially fatal drug interaction could occur.
Grapefruit juice and grapefruit can also interact negatively with this medication and lead to potentially dangerous effects.
Is trazodone addictive?
This medicine has a slight potential to be addictive. Also, if you were taking it, and suddenly stopped doing it, you may experience some withdrawal symptoms. Therefore, it is recommended to take this medication exactly as prescribed by your doctor and to stop this medication, decrease it slowly.
Is trazodone addictive? + Uses, Drug Interactions, Side Effects, Source: https://www.yourhealthremedy.com/health-tips/is-trazodone-addictive/
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