Is Flexeril addictive? + Uses, drug interactions, side effects

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It's addictive Flexeril + uses, drug interactions, side effects

Flexeril is the brand name of a medication called cyclobenzaprine that is part of a class of medications called skeletal muscle relaxants.

This medication works by blocking nerve impulses that are sent to the brain. It has no activity in the central nervous system or any action within the neuromuscular junctions (a synapse between a skeletal muscle and a motor neuron).


It is usually used (along with rest and physical therapy) to relieve muscle spasms. This helps reduce stiffness, pain or discomfort caused by injuries or strains in the muscles.

Note – this medication It is not designed for long-term use, and patients should follow the regimen provided by their doctor.

In addition, it is prescribed off the label to treat fibromyalgia, a common and complex chronic pain. disorder what causes widespread pain. In addition to generalized pain, people with fibromyalgia may experience:

headaches increased sensitivity to pain; a digestive condition that causes pain and swelling of the stomach (irritable bowel syndrome); Problems with mental processes, such as: problems with concentration and memory; difficulty sleeping (insomnia); muscular stiffness; Extreme tiredness (fatigue).

It is not known exactly why some individuals develop fibromyalgia, but there are likely to be several factors involved. They include:

Emotional stress: can create long-range effects with which the body faces for years. In addition, it has been strongly associated with post-traumatic stress disorder; trauma: people who experience physical trauma can develop fibromyalgia; Genetics: according to some studies, genetic mutations may play a role in the development of this condition. Infections: Previous illnesses can worsen some symptoms of this condition.


This medicine is available as a prolonged-release capsule and a tablet to take by mouth. The extended-release capsule is usually taken with or without food once a day. The tablet is usually taken without or with food 3 times a day.

Important note: Do not take this medication for more than 21 days without consulting your health care provider.

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Side effects and precautions of cyclobenzaprine

Common side effects It can include:

feeling tired; dry throat; dry mouth; gas; blurry vision; muscular weakness; constipation; Diarrhea; nausea; stomach ache; loss of appetite; dizziness; drowsiness.

Rare side effects It can include:

Fainting; uneven heartbeats; sudden and severe headaches; feel dizzy; accelerated heartbeat; balance problems; Confusion; weakness on one side of the body; Eye sight problems; lack of coordination; problems with speech; weakness; pain that extends to the shoulder or arm; yellowing of the skin or eyes; perspiration; clay-colored stools; Chest pain; seizures (convulsions); hallucinations (see things); dark urine; unusual thoughts low fever; Easy bruising or bleeding

It can also cause a life-threatening condition called serotonin syndrome. This happens when the drugs cause too much serotonin (a monoamine neurotransmitter) to accumulate in the human body. Symptoms of serotonin syndrome usually begin within a few hours of taking a new medication that affects serotonin levels. They can include:

headaches Confusion; tremor; restlessness; high cardiac rhythm; agitation; intense sweating dilated pupils; Diarrhea; goosebumps; trembling twisted muscles or loss of muscle coordination; vomit nausea; Changes in blood pressure.

The milder forms of serotonin syndrome may disappear after a day of stopping medications that cause symptoms and, on occasion, taking medications that block serotonin.

The pregnancy

Talk to your health care provider before using this medication because there are no adequate and well-controlled studies in pregnant women. Also, it is not known if it passes into breast milk or if it could harm your baby.

Alcohol interaction

This drug can increase the effects of alcohol and increase the sedative effects of both, causing dizziness and drowsiness. In addition, side effects increase for adults over 65 because aging decreases the body's ability to metabolize alcohol, therefore, remains in the body of the person for longer.

In addition, people with hepatic impairment are usually more susceptible to drugs with potentially sedating effects.

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Drug interactions

Many drugs can interact with this medicine. Therefore, inform your health professional if you are using:

glycopyrrolate, a medicine of the muscarinic anticholinergic group; scopolamine, a medication used to treat nausea and postoperative dizziness; guanetidine, an antihypertensive medication that reduces the release of catecholamines; metscopolamine, a medicine used with other medications to treat a peptic ulcer; mepenzolate, a post-ganglionic parasympathetic inhibitor; dimenhydrinate, an over-the-counter medication used to treat nausea and motion sickness; tramadol (Ultram); benztropine, an anti-Parkinson and anticholinergic agent; atropine (donnatal); medicines for the irritable bowel, such as – propantheline (Pro-Banthine), hyoscyamine (Cystospaz, Anaspaz, Levsin) or dicyclomine (Bentyl); a bronchodilator, such as tiotropium (Spiriva) or ipratropium (Atrovent); urinary medicines, such as – solifenacin (Vesicare), tolterodine (Detrol), oxybutynin (Oxytrol, Ditropan), flavoxate (Urispas) or darifenacin (Enablex).

Also, do not take this medication if you have used monoamine oxidase inhibitors in the past 2 weeks because life-threatening side effects may occur. Inhibitors of monoamine oxidase include: selegiline (Emsam, Eldepryl), phenelzine (Nardil), tranylcypromine (Parnate) or isocarboxazide (Marplan). Other medications may interact with this medication, including herbal products and vitamins.

Is Flexeril addictive?

This medication is not considered physically addictive, as are narcotic analgesics. However, it is possible to become psychologically dependent on this medication. Actually, this means that you may feel that you need to use this medicine to feel pain-free, especially if you have been using it for more than a month.


At higher doses, this medication can cause a neurological condition in which patients lose control of their muscle movements, called ataxia. In addition, when abused, it can induce moderate anticholinergic effects, which means that it leads to an increase in parasympathetic capacity. Activity in the body This can lead to mental and physical deterioration.


It is recommended to store this medication at 25 ° C (77 ° F).


Is Flexeril addictive? + Uses, Drug Interactions, Side Effects, Source:

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