Intuniv vs Strattera – Comparison of uses and side effects

Filed in: Health Tips.

Intuniv vs Strattera - Comparison of uses and side effects

Intuniv

It is the brand name of a drug called guanfacine that is part of a group of drugs called centrally acting alpha 2A adrenergic receptor agonists.

Applications

Note – must be used as part of a comprehensive treatment program that generally includes psychological, educational and social therapy.

This medication is used to treat attention deficit hyperactivity disorder in children who are at least 6 years old.

In addition, it is used to treat high blood pressure.

Its effectiveness and safety in children under 6 years have not been established. Therefore, do not give this medication to a child under 6 years of age.

Mechanism of action

The medication works by affecting the receptors in the brain in a way that helps the person suffering the symptoms of ADHD symptoms, such as emotional sensitivity, hyperactivity and social aggression.

Also, unlike other medications for ADHD, it is said that this alpha 2A adrenergic receptor agonist is safer because it is not a central nervous system stimulant medication.

Dosage

Notes – It is in the form of a pill, however, unlike other ADHD medications, it can not be chewed, crushed or broken and must be swallowed whole.

The usual recommended dose is 1 to 4 mg per day. A dose lasts 12 hours, but can have some effect up to 24 hours.

Alcohol

Avoid alcohol while taking this alpha 2A adrenergic receptor agonist because alcohol may increase the risk of side effects, especially drowsiness.

Side effects and precautions

Common side effects may include:

irritability; dry mouth; vomiting drowsiness mild dizziness slight slow heartbeat.

Less common side effects may include:

difficulty to sleep; weakness; a feeling of dizziness as if he could faint; dry mouth; Chest pain; stomach ache; sedation; constipation; rapid heartbeat; nausea; fatigue; hallucinations; low blood pressure.

Contraindications

To make sure you can take this alpha 2A adrenergic receptor agonist safely, tell your healthcare provider if you have any of these other conditions:

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coronary artery disease; kidney disease; a history of apoplexy; heart block; low blood pressure; liver disease; if you have recently had a heart attack; heart disease.

Drug interactions

It can affect how other medications work, and other medications can affect the way this alpha 2A adrenergic receptor agonist works. Tell your doctor if you take:

valproic acid; antipsychotics; medications that can affect the metabolism of enzymes; ketoconazole; cymbalta; medications for high blood pressure; barbiturates; sedatives benzodiazepines.

Pregnancy and lactation

Belongs to the pregnancy category B of the FDA. This means that this medication is not expected to be harmful to the fetus.

It is not known whether this alpha 2A adrenergic receptor agonist passes into breast milk or if it could adversely affect a breastfeeding baby. Tell your doctor if you are breast-feeding a baby.

Strattera

It is the brand name of a medicine called atomoxetine, which belongs to a group of drugs called selective norepinephrine reuptake inhibitors.

Applications

This prescription medication is used to treat attention deficit hyperactivity disorder.

This drug is produced by Eli Lilly and Company. It was originally approved by the Food and Drug Administration of the United States in 2002.

Mechanism of action

It works by increasing the levels of norepinephrine, the main main transmitter of most postganglionic sympathetic fibers.

Dosage

The usual recommended initial dose is 40 mg per day orally. The dose is increased to 80 mg per day after a minimum of 3 days.

Pregnancy and lactation

The medication can pass into breast milk and adversely affect the breastfed baby. In addition, there are no studies to determine if this selective norepinephrine reuptake inhibitor is safe during pregnancy.

Side effects and precautions

Common side effects may include:

loss of appetite; feeling tired; problems to have an erection; constipation; dry mouth; dizziness; problems urinating; Stomach ache; nausea; vomiting mood changes.

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Less common side effects may include:

dark urine; pain when urinating; new behavior problems; a feeling that you may faint; hostility; The erection is painful or lasts more than 4 hours; hallucinations; difficulty breathing; paranoia; Chest pain; jaundice (yellowing of the skin or eyes).

Alcohol

Avoid consuming alcoholic beverages while taking this selective norepinephrine reuptake inhibitor, since alcohol consumption can substantially increase the risk of side effects.

Drug interactions

You may interact negatively with other medications, especially:

Cymbalta (duloxetine); Wellbutrin (bupropion); Lexapro (escitalopram); Abilify (aripiprazole); Celexa (citalopram); Zoloft (sertraline); Prozac (fluoxetine); Benadryl (diphenhydramine)

Contraindications

Before taking this selective norepinephrine reuptake inhibitor, tell your healthcare provider if you have:

serious problems of the heart; pheochromocytoma; Narrow angle glaucoma.

Bottom line – Intuniv vs Strattera

Intuniv (active ingredient – Guanfacine) is a non-stimulant treatment for attention deficit hyperactivity disorder. It is a form of long-acting guanfacine. In addition, it can be useful for the estimated 25 to 30% of children with ADHD who do not benefit from stimulant medications.

In addition, this medication works somewhat more than traditional non-stimulants, such as Strattera, and somewhat less than stimulants, such as Adderall and Ritalin.

Strattera (active ingredient – atomoxetine) is a medication used to treat attention deficit hyperactivity disorder. It is part of a class of medications known as selective norepinephrine reuptake inhibitors.

According to a 2013 study, Intuniv appears to be more effective than Strattera for the treatment of attention deficit hyperactivity disorder.

Regarding its price, the average retail price of 30 tablets of Intuniv 1 mg is $ 320, while the average retail price of 30 capsules of Strattera 40 mg is $ 450.

Referenceshttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2935643/https://www.ncbi.nlm.nih.gov/pubmed/23683139http://www.ema.europa.eu/docs/en_GB/document_library/EPAR_-_Public_asses

Intuniv vs Strattera – Comparison of uses and side effects, Source: https://www.yourhealthremedy.com/health-tips/intuniv-vs-strattera/

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