Humira vs Enbrel – Uses, doses, side effects, differences

Filed in: Health Tips.

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Humira

It is a brand name of a medication called adalimumab that works by blocking the production of TNF-alpha to reduce inflammation of the skin and joints.

The Food and Drug Administration originally approved this drug in 2002. It is produced by Abbott Laboratories, a global health care company headquartered in Lake Bluff, Illinois, USA. UU

Applications

Is typically prescribed for:

Juvenile idiopathic arthritis; Ankylosing spondylitis (a type of arthritis that affects the spine); psoriasic arthritis; Rheumatoid arthritis.

In addition, it is used to treat the symptoms of active Crohn's disease in patients who have not received help with other medications, such as infliximab. Crohn's disease is an inflammatory disease mediated by the immune system that belongs to a larger group of diseases called inflammatory bowel diseases.

Dosage

the dose schedule of this medication It is very variable and depends on the condition of the patient. For example, you may need an injection every seven days or you may need an injection every two days.

Note: Depending on the condition being treated, patients may take between 1 and 3 months to observe some improvements.

Side effects and precautions of adalimumab

Common side effects may include:

eruption; Headaches; bruising, redness, swelling or itching at the injection site; a sore throat pain of sinusitis; a stuffy nose

Rare side effects It can include:

feeling full after eating only a small amount of food; fatigue; high cardiac rhythm; unexplained weight loss; upper stomach pain; night sweats; dark urine; fever; yellowing of the skin or eyes; pain in the upper part of the stomach that can spread to the shoulder; burning when urinating; clay-colored stools; Diarrhea; vomit dizzy; bruising easily; loss of appetite; Eye sight problems; pale skin; a tingling sensation; worsening of psoriasis; short of breath.

To make sure this medication is safe for you, tell your health care professional about all of your health conditions, even if:

have or have had hepatitis B; they are being treated for an infection; have symptoms of an infection; have an infection or have had some type of cancer; they have infections that keep coming back; have many infections; have or had heart failure; have type 2 Mellitus diabetes; is allergic to latex, rubber, or any ingredient found in this medication; to have a baby and you were using this medicine during your pregnancy; are pregnant or plan to get pregnant; you have recently received or are scheduled to receive a vaccine; have a disease of the nervous system, such as: Guillain-Barré syndrome or multiple sclerosis are scheduled for major surgery; live or have lived in an area where there is a greater risk of getting certain types of fungal infections, such as: coccidioidomycosis, histoplasmosis (this disease mainly affects the lungs) or blastomycosis; have tuberculosis or have been in close contact with someone with tuberculosis.

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Alcohol

Avoid alcohol while you are taking adalimumab.

Enbrel

It is the brand of an injectable. drug called etanercept that works by blocking the tumor necrosis factor alpha, a substance in the human body that causes inflammation, among other functions.

The drug is produced by Amgen, Inc., a US biopharmaceutical company based in Thousand Oaks, California, USA. UU It was originally approved by the Food and Drug Administration in 1998.

Important note: people who use this type of medication have a high risk of reactivation of a latent TB infection, according to the Centers for Disease Control and Prevention.

Applications

It is normally used to treat the following conditions:

severe chronic psoriatic arthritis in children aged 4 to 17 years; psoriatic arthritis in adults; active ankylosing spondylitis; moderate to severe rheumatoid arthritis in adults; juvenile idiopathic arthritis of moderate to severe in children; Psoriasis in moderate to severe chronic plaque in adults.

Dosage

The usual recommended dose is 50 mg injected twice a week in adults.

Side effects and precautions of etanercept

Common side effects may include:

headaches Mild nausea; weakness; vomit a runny nose; Diarrhea; cough; stomach ache; weight changes; acidity; Discomfort at the injection site.

Rare side effects may include:

Bleeding; seizures dizziness; bruising changes in vision; a butterfly-shaped rash on the nose and cheeks; Chest pain; patched skin color; swelling; a cough in progress unusual thoughts or behaviors; problems swallowing; difficult breathing; tarry stools; body pain; cough with blood or mucus; Inflamed glands; Confusion; rapid weight gain; neck stiffness; a sore throat mood swings.

Note: Because this medication negatively affects your immune system, serious infections can occur in people who use it.

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To make sure this medication is safe for you, tell your health care provider if you have or have ever had the following:

Diabetes mellitus type 2; seizures any type of recurrent infection; tuberculosis; HIV or AIDS; Any cut or open sores; pain when urinating; any disease that affects the nervous system, such as: multiple sclerosis or Guillain-Barré syndrome; Diarrhea; congestive heart failure; asthma or other respiratory disorder; Hepatitis B heart failure; liver disease; inflammation of the nerve that sends messages from the eye to the brain (optic neuritis); inflammation of the spinal cord that can cause unusual sensations (transverse myelitis); if you have recently been vaccinated with Bacille Calmette-Guerin (BCG); if you are scheduled to receive a vaccine; If you are allergic to latex rubber.

Other drugs that block TNF alpha include:

infliximab (Remicade); golimumab (simponi); certolizumab (cimzia).

Humira vs Enbrel – Differences

It is the brand name of a drug called adalimumab, a tumor necrosis factor blocker that reduces the effects of a substance in the human body that can cause inflammation.

This injectable medication is usually used to treat adults with inflammatory conditions, such as: Crohn's disease, rheumatoid arthritis, suppurative hidradenitis, ankylosing spondylitis, plaque psoriasis, and ulcerative colitis.

Enbrel (active ingredient – etanercept) is a medicine that belongs to the class of drugs called tumor necrosis factor inhibitors or biological response modifiers.

This prescription medication is usually used to treat inflammatory conditions, as – psoriatic arthritis, severe rheumatoid arthritis, idiopathic arthritis, plaque psoriasis and ankylosing spondylitis.

Referenceshttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3740810/https://www.enbrel.com/hcp/why-enbrel/efficacy-rheumatoid-arthritishttps://www.fda.gov/ohrms/dockets/ac/01/briefing/3779b2_02_immunex.pdfhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002485/

Humira vs Enbrel – Uses, doses, side effects, differences, Source: https://www.yourhealthremedy.com/health-tips/humira-vs-enbrel/

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