Gammagard vs Gamunex – Comparison of side effects and uses

Filed in: Health Tips.

Gammagard vs Gamunex - Comparison of side effects and uses

Gammagard

It is the brand name of a medicine called immunoglobulin. It is a sterile solution made of human plasma.

This medicine has antibodies that help your body protect itself from various diseases.

Applications

It is used to strengthen the body's natural defense system and to reduce the risk of infection in people with a weakened immune system, such as those who suffer from Chronic lymphocytic leukemia.

This medication is also used to treat chronic inflammatory demyelinating polyneuropathy, as well as to increase platelets in patients with idiopathic thrombocytopenic purpura and to prevent an aneurysm caused by a weakening of the main artery.

Dosage

The usual recommended dose is 300 to 600 mg / kg every 3 to 4 weeks depending on the clinical response.

Side effects Y Precautions

Common side effects may include:

lower chest pain; a mild headache, redness, warmth, or tingling sensation; muscle cramps; dizziness; Back pain; feeling tired

Rare side effects It can include:

urinate little or nothing; problems with vision or balance; jaundice (yellowing of the skin or eyes); speaks confused; dark urine; rapid weight gain; sudden numbness or weakness; fast heart rate; vomiting swelling or redness in one or both legs; nausea; coughing up blood; greater sensitivity to light; fast breathing; neck stiffness; wheezing severe headaches; a sudden cough mouth ulcers; high fever; Appearance blue in your fingers or toes; blue lips; difficulty breathing; Chest pain.

To make sure this medication is safe for you, tell your health care provider if you have:

a history of blood clots; a history of apoplexy; kidney disease; a disorder of the blood vessels; diabetes; blood circulation problems; a serious infection called sepsis; heart disease; if you use estrogen; if you are dehydrated hyperproteinemia (the state of having excessively high levels of proteins in the blood); if you have been in bed due to a serious illness; paraproteinemia (the presence of excessive amounts of single monoclonal gammaglobulin in the blood); if you are using a catheter; If you are 65 or older.

Alcoholbeer alcohol

Do not consume alcoholic beverages while using this medication, as the known side effects can increase considerably.

Drug interactionspills (2)

You may interact negatively with other medications, especially:

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gabapentin; aspirin; lisinopril; Benadryl (diphenhydramine); prednisone; clonazepam; Symbicort (budesonide / formoterol); Cymbalta (duloxetine); Synthroid (levothyroxine); levothyroxine; Tylenol (acetaminophen); metformin; trazodone; Omeprazole; Zofran (ondansetron); Topamax (topiramate); Singulair (montelukast).

Pregnancy and lactation

It is not known if this medicine passes into breast milk. Consult your health care provider before breast-feeding.

Also, during pregnancy, this medication should be used only when clearly necessary, as it can affect the unborn baby in a negative way.

Gamunex

It is the brand name of a drug called immunoglobulin, a formulation that can meet the needs of a variety of types of patients with IDP, CIDP and ITP.

Applications

It is used in people with a certain blood problem to raise platelet levels. In addition, it is used in people with a certain nervous system problem, such as chronic inflammatory demyelinating polyneuropathy.

Dosage

The medicine is given as an injection in the office of your health care provider.

Side effects and precautions

Common side effects may include:

muscle cramps; a mild headache minor chest pain; dizziness; redness or tingling sensation; Back pain; feeling tired

Rare side effects may include:

red or pink urine; urinate less than usual; a sudden cough vomiting seizures (convulsions); purple spots on the skin; drowsiness; a feeling that you may faint; coughing up vomiting that looks like coffee beans; chest tightness; Confusion; sudden numbness or weakness; feeling short of breath; humor changes; greater sensitivity to light; nausea; black or tarry stools; cold; wheezing weight gain; dark colored urine; increased thirst; unusual bleeding (nose, vagina, mouth or rectum); neck stiffness; Sharp red spots under the skin; pale or yellowish skin; heat or swelling in one or both legs; problems with vision or speech; fast breathing; severe and sudden headache

To make sure this medication is safe for you, tell your health care provider if you have:

kidney disease; blood circulation problems; diabetes; a disorder of the blood vessels; a serious infection called sepsis; heart disease; hyperproteinemia (too much protein in the blood); a history of blood clots; a history of apoplexy; paraproteinemia (abnormal proteins in the blood); if you use birth control pills; if you are 65 or older; if you are using a catheter; if you have been in bed due to a serious illness; If you are dehydrated.

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Alcohol

Do not consume alcoholic beverages while using this medication, as the known side effects can increase considerably.

Drug interactions

You may interact negatively with other medications, especially:

medications used to treat ulcerative colitis, such as – sulfasalazine (bluefidine) or mesalamine (Pentasa); Lithium (Lithobid); antiviral medications, such as adefovir (Hepsera), acyclovir (Zovirax), ganciclovir (Cytovene), foscarnet (Foscavir), valganciclovir (Valcyte), or valaciclovir (Valtrex); Intravenous antibiotics, such as – amikacin (Amikin), amphotericin B (Amphotec, Abelcet), capreomycin (Capastat), bacitracin (Baci IM), kanamycin (Kantrex) or vancomycin (Vancocin); tamiflu; methotrexate (Trexall); medicines for cancer, such as carmustine (Gliadel), aldesleukin (Proleukin), oxaliplatin (Eloxatin), ifosfamide (Ifex) or tretinoin (Vesanoid); medications used to prevent rejection of organ transplants, such as cyclosporine (Gengraf, Sandimmune) or tacrolimus (Prograf); forteo; medicines for pain or arthritis, such as acetaminophen (Tylenol), aspirin (Anacin), naproxen (Aleve, Treximet), ibuprofen (Advil), indomethacin (Indocin), diclofenac (Arthrotec, Voltaren, Pennsaid, Solareze), or meloxicam ( Mobic).

Pregnancy and lactationpregnant

It is not known whether this medication passes into breast milk or if it could adversely affect a baby. Do not use this medication without telling your healthcare professional if you are breast-feeding a baby.

Also, it is not known exactly if this medication will harm the unborn baby. Tell your healthcare professional if you are pregnant or plan to become pregnant while using this medication.

Bottom line – Gammagard vs Gamunex

Gammagard (active ingredient – immunoglobulin) is a sterilized solution that is made of human plasma. This medicine contains antibodies to help your body protect itself against infections from specific diseases. diseases.

Gamunex-C (active ingredient – immune globulin) is a medicine used to treat a condition called primary immune deficiency. It can also be used to treat other conditions, as determined by your doctor.

In conclusion, both drugs contain the same active ingredient and the main difference between them is that the immunoglobulin content of Gamunex-C is higher in 9 μg / ml than in Gammagard.

Referenceshttp://www.gammagard.com/MMN/healthcare-professionals/gammagard/pivotal-study-design.htmlhttps://www.ncbi.nlm.nih.gov/pubmed/25865232https://www.sciencedirect.com/science/article/pii/S0149291896801925

Gammagard vs Gamunex – Comparison of side effects and uses, Source: https://www.yourhealthremedy.com/health-tips/gammagard-vs-gamunex/

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