Etodolac vs Meloxicam – Comparison of side effects and uses

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Etodolac vs Meloxicam - Comparison of side effects and uses

Etodolaco

It is a medicine that belongs to the group of medicines known as non-steroidal anti-inflammatory drugs. It can be found under the following brands: Lodine and Lodine XL.

The medication works by blocking substances called prostaglandins that cause pain and inflammation.

Applications

This prescription medication is used to treat pain, swelling, tenderness and stiffness caused by rheumatoid arthritis and osteoarthritis.

Dosage

For rheumatoid arthritis, the usual recommended dose in adults is 300 mg orally 2 to 3 times per day. The total recommended daily dose should not exceed 1200 mg.

For osteoarthritis, the usual recommended dose in adults is 300 mg orally 2 to 3 times per day. The total daily dose should not exceed 1200 mg.

The effect of this non-steroidal anti-inflammatory drug has an average duration of 4 to 12 hours.

Side effects and precautions

Common side effects may include:

weakness; indigestion; dizziness; stomach ache; a runny nose; vomit a sore throat nausea; eruption; gas; constipation headaches; Itch; Diarrhea.

Rare side effects may include:

rapid weight gain; changes in vision; bloody or tarry stools; shortness of breath tired feeling cough vomiting that looks like coffee beans; problems to concentrate; jaundice (yellowing of the skin or eyes); high heart rate; painful or difficult urination; loss of appetite; stools of clay color; pale skin; upper stomach pain; burning in your eyes; swelling of your feet, face, tongue or ankles; a rash on the red skin that spreads and causes blistering and peeling; little or no urination.

To make sure this non-steroidal anti-inflammatory drug is safe for you, tell your healthcare provider if you have:

a history of stomach ulcers or bleeding; asthma; kidney disease; a history of stroke, heart attack or blood clot; if you smoke tobacco; if you are regularly exposed to tobacco smoke (second-hand smoke); liver disease; Diabetes mellitus type 2; fluid retention; high blood pressure; heart disease; High levels of LDL and total cholesterol.

Drug interactions

You may interact negatively with other medications, especially:

an anticoagulant, such as warfarin (Coumadin); eliquis; an antidepressant, such as duloxetine (Cymbalta), citalopram (Celexa), escitalopram (Lexapro), paroxetine (Paxil), fluvoxamine (Luvox) or venlafaxine (Effexor); Methotrexate (Rheumatrex, Trexall); Ciclosporin (Gengraf, Neoral, Sandimmune); steroids (prednisone and others); a diuretic (water pills), such as – furosemide (Lasix); Lithium (Eskalith, Lithobid); an ACE inhibitor, such as captopril (Capoten), benazepril (Lotensin), fosinopril (Monopril) or ramipril (Altace); Non-steroidal anti-inflammatory drugs, such as – flurbiprofen (Ansaid), aspirin, diclofenac (Cataflam, Voltaren), mefenamic acid (Ponstel), ketorolac (Toradol), naproxen (Aleve, Naprosyn), nabumetone (Relafen) or piroxicam (Feldene); Digoxin (a medicine used to treat various heart conditions).

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Pregnancy and lactation

It is not known exactly if this non-steroidal anti-inflammatory drug passes into breast milk or if it could adversely affect the baby. Therefore, do not use it without telling your health care provider if you are breast-feeding.

More importantly, it can be harmful to an unborn baby, especially if you are taking this nonsteroidal anti-inflammatory drug during the last three months of pregnancy.

Alcohol

Do not drink alcohol while taking this medication, as alcohol may increase the risk of side effects, such as stomach bleeding.

Meloxicam

It is the name of a medication that belongs to a family of medicines collectively called non-steroidal anti-inflammatory drugs. It can be found under the Mobic brand.

It works by blocking the action of cyclooxygenase (COX). This enzyme participates in the production of prostaglandins, the chemicals responsible for causing inflammation and pain in the body.

Applications

It is used to relieve the swelling and pain of rheumatoid arthritis and osteoarthritis. In addition, this prescription medication is used to treat ankylosing spondylitis.

Dosage

The usual recommended dose is 0.09 mg / lb of body weight only on the first day of treatment. Then, according to the individual response, the patient should take the lowest effective dose for the shortest duration.

Important note: your doctor may prescribe another medication for you to take along with this nonsteroidal anti-inflammatory drug to protect your stomach from irritation.

Side effects and precautions

Common side effects may include:

dizziness; Stomach ache; nausea; Diarrhea; edema; gas; stomach ache; infection of the upper respiratory tract; digestive problems; acidity headaches; symptoms similar to the flu.

Less common side effects It can include:

Muscle pain; cracks in the skin; hoarseness; loosening of the skin; Scaly skin; loss of body heat; vomiting blood that looks like coffee beans; tarry stools; unusual tiredness severe stomach pain; swelling around the eyes, lips, face or tongue; continuous vomiting; fever with or without chills; weak pulse a decrease in the amount of urine; red and swollen skin; Irritated eyes; problems with swallowing; bad smell of breathing.

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Contraindications

Do not take this medication if:

have higher potassium levels in the blood than normal; have any type of allergic reaction; have a bleeding disorder; have experienced nasal polyps or asthma; have intestinal ulcers; is allergic to any of the ingredients of this non-steroidal anti-inflammatory drug; has inflammatory bowel disease; have reduced liver function; have reduced kidney function; have recently had coronary artery bypass graft surgery; they are under 18 years old; You have uncontrolled heart failure.

Drug interactions

Can interact negatively with others medicinesespecially

cholestyramine (Questran); lithium (Eskalith, Lithobid); warfarin; warfarin (Coumadin); ACE inhibitors, such as – captopril (Capoten), enalapril (Vasotec) or lisinopril (Prinivil); methotrexate (Rheumatrex, Trexall); Aspirin (Ecotrin) and other non-steroidal anti-inflammatories drug; diuretics, such as – furosemide (Lasix) or thiazides (hydrochlorothiazide); cimetidine (Tagamet); sodium erythorbate; oxymetazoline; digoxin (Digitek, Lanoxin); claritin; cyclosporine (Gengraf, Neoral, Sandimmune).

Pregnancy and lactation

The use of this medication during pregnancy is not recommended unless your doctor prescribes it, especially if you are pregnant for 30 weeks or more. In addition, it can pass into breast milk and harm the baby. Therefore, avoid this nonsteroidal anti-inflammatory drug if you are breast-feeding a baby.

Alcohol

It is a non-steroidal anti-inflammatory drug, therefore, it should not be taken with alcohol due to the risk of bleeding in the stomach.

Final result – Etodolac vs Meloxicam

Etodolac (brand names – Lodine and Lodine XL) is a nonsteroidal anti-inflammatory drug that is used to treat osteoarthritis and rheumatoid arthritis. This medicine works by reducing the hormones that cause inflammation and pain in the human body.

Meloxicam (brand name – Mobic) is a non-steroidal anti-inflammatory drug that is used for pain due to osteoarthritis.

Referenceshttps://www.ncbi.nlm.nih.gov/pubmed/2525983https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164827/https://www.ncbi.nlm.nih.gov/pubmed/9035017

Etodolac vs Meloxicam – Comparison of side effects and uses, Source: https://www.yourhealthremedy.com/harmful-compounds/e-dodolac-vs-meloxicam/

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