Entyvio vs Humira – Comparison of side effects, uses, cost

Filed in: Health Tips.

Entyvio vs Humira - Comparison of side effects, uses, cost

Entyvio

It is the brand name of a medication called vedolizumab, which belongs to a group of drugs known as integrin receptor antagonists.

Mechanism of action

It works in a similar way to the natural antibodies produced by the human immune system.

Applications

This prescription medication is used in adults with moderate to severe Crohn's disease, a chronic inflammatory bowel disease characterized by inflammation of the gastrointestinal tract.

In addition, this medication is used in adults with moderate to severe ulcerative colitis, a severe inflammatory bowel disease that increases the risk of colon cancer.

Ulcerative colitis and Crohn's disease are the two most common types of inflammatory bowel diseases and are described by long-term inflammation of different parts of the intestine.

Important note – This medication is commonly prescribed for adults with moderate to severe inflammatory bowel disease for whom other corticosteroids, anti-TNF drugs or immunomodulatory drugs do not work well enough.

Dosage

The usual recommended dose is 300 mg administered by intravenous infusion by a doctor at 0 (zero), 2 (two) and 6 (six) weeks. If there has been a good response to the first doses, you can continue this medical treatment with additional doses every 8 weeks.

Contraindications

Before receiving this medication, inform your medical professional if:

have tuberculosis; have liver problems; you have recently received or are scheduled to receive a vaccine; have an infection

Side effects and precautions

Common side effects may include:

a sore throat fever; feeling of nausea; pain in the arms or legs; sinusitis pain; the common cold; Back pain; headaches joint pain; Stuffy nose Itching.

Less common side effects may include:

diarrhea that is watery or bloody; skin sores; clay-colored stools; it oozes around the anal area; loss of appetite; severe diarrhea; unexplained weight loss; body pain; upper stomach pain; pain when swallowing; dark urine; jaundice (yellowing of the skin or eyes); Ulcers in the mouth and throat.

Alcohol

Avoid drinking alcoholic beverages while taking this medication, since alcohol consumption can substantially increase the risk of serious side effects.

Drug interactions

Can interact negatively with others medicinesespecially

methotrexate; dicyclomine; Norco (acetaminophen / hydrocodone); gabapentin; vemlidy; prednisone; Imuran (azathioprine); Zofran (ondansetron); Lialda (mesalamine); zolpidem; lisinopril; tramadol; metformin; Harvoni; potassium chloride; pantoprazole; Omeprazole

Read Also  The 11 highest iron nuts to fight anemia

Pregnancy and lactation

There are no well-done studies to determine if this the medication is safe to use during pregnancy. Count your health care provider who is pregnant or planning to become pregnant before using this medicine.

It is not known exactly if this medicine passes into human breast milk or if it could affects negatively A breastfed baby. Tell your health care provider that you are breast-feeding a baby before using this medicine.

Humira

It is the brand name of a medication called adalimumab, which is part of a class of drugs called tumor necrosis factor inhibitors.

Mechanism of action

This medication works by reducing inflammation and decreasing the progression of inflammatory conditions by attacking a substance produced by the immune system, called TNF.

It is manufactured by Abbott Laboratories, a leading manufacturer of health care products. It was approved for the first time by the US Food and Drug Administration. UU In 2002.

Applications

It is used to treat certain types of arthritis, Crohn's disease, plaque psoriasis, ulcerative colitis (a long-term condition that causes inflammation and ulcers of the rectum and colon), ankylosing spondylitis (an inflammatory disease that can cause some of the vertebrae in the spine to fuse, and a chronic inflammatory skin disease, called hidradenitis suppurativa.

Dosage

For patients with Crohn's disease and ulcerative colitis, the usual recommended initial dose is 160 mg in the first two days of treatment. Then, the treatment is continued for 2 weeks with 80 mg.

For people with ankylosing spondylitis, rheumatoid arthritis and psoriatic arthritis, the usual recommended dose is 40 mg injected under the skin every two weeks.

Alcohol

Avoid drinking alcoholic beverages while taking this medication, since alcohol consumption can substantially increase the risk of serious side effects.

Contraindications

To make sure this medication is safe for you, tell your healthcare professional if you have ever had:

hepatitis B; any tingling or numbness; kidney disease; Cancer; if you are scheduled to receive any vaccine; a nervous-muscular disorder, such as: multiple sclerosis or Guillain-Barré syndrome; if you have recently received a vaccine; chronic infections; congestive heart failure; An allergy to latex rubber.

Read Also  Thymus versus thyroid: location, functions, disorders, differences

Pregnancy and lactationpregnant

It is not known exactly if this medicine passes into human breast milk or if it could adversely affect a breastfed baby. Tell your health care provider that you are breast-feeding a baby before using this medicine.

According to some studies, this medication could adversely affect a developing fetus. Tell your health care provider that you are pregnant or planning to become pregnant before using this medicine.

Side effects and precautions

Common side effects may include:

redness; swelling headaches; nausea bruises; upper respiratory infections; Back pain; eruption; Itch.

Less common side effects may include:

problems swallowing; urticaria; swelling of the face, ankles, feet or lower legs; Chest pain; unusual bleeding or bruising; pale skin; shortness of breath numbness; a sore throat scaly patches; dizziness; new pain in the joints; Itch; protuberances filled with pus; cold; Eye sight problems; fever; rash on the arms or cheeks; difficulty breathing; Weakness in the legs

Drug interactions

You may interact negatively with other medications, especially:

Benadryl (diphenhydramine); Cymbalta (duloxetine); Plaquenil (hydroxychloroquine); Aleve (naproxen); cyclobenzaprine; levothyroxine; Tylenol (acetaminophen); amoxicillin; Imuran (azathioprine); Lyrica (pregabalin); trazodone; Kojic acid; azathioprine; Omeprazole; meloxicam; methotrexate; Nexium (esomeprazole); metformin; Celebrex (celecoxib); lisinopril; prednisone; tramadol; ibuprofen; Gabapentin

In a few words – Entyvio vs Humira

Entyvio (active ingredient – vedolizumab) is a medication used for the treatment of adults with Crohn's disease of moderate to severe activity and ulcerative colitis of moderate to severe activity. The mechanism of action seems to be restricted to the intestine without a complete abrogation of the host's immune system, preserving mucosal immunity.

Humira (active ingredient – adalimumab) is a medication used to relieve the symptoms of Crohn's disease, certain types of arthritis and plaque psoriasis.

According to the data, Entyvio requires a good amount of time to work, while Humira generally works faster.

Regarding its price, the average retail price of 3 vials of Entyvio 300 mg is $ 17,300, while the average retail price of a cardboard box (2 pens) of Humira 40 mg / 0.8 ml is $ 4,900.

Referenceshttps://clinicaltrials.gov/ct2/show/NCT02674308https://www.ncbi.nlm.nih.gov/pubmed/25341118http://gut.bmj.com/content/early/2016/02/18/gutjn

Entyvio vs Humira – Comparison of side effects, uses, cost, source: https://www.yourhealthremedy.com/health-tips/entyvio-vs-humira/

You May Also Like:
    Salmonella vs E. coli – Symptoms, Causes, Treatment, Differences, Prevention
    Salmonella vs E. coli - Symptoms, Causes, Treatment, Differences, Prevention
    Salmonella It is an extremely common type of bacteria. There are more than 2,500 strains of this type of bacteria, however, only less than

    Horizant vs Gabapentin – Which is more effective for RLS (Restless Legs Syndrome)?
    Horizant vs Gabapentin - Which is more effective for RLS (Restless Legs Syndrome)?
    Restless legs syndrome (RLS), also known as Willis-Ekbom disease, is a disorder of the part of the nervous system that causes the need to

    Secretagogue One vs Gold – Differences
    Secretagogue One vs Gold - Differences
    MHP Secretagogue-One It is a patented combination of precursor nutrients and amino acids that stimulate the natural production of insulin-like growth factor 1 (IGF-1)

    10 essential oils for carpal tunnel syndrome
    Young Living 10 essential oils for carpal tunnel syndrome
    Carpal tunnel syndrome is a disorder of the hand and wrist, caused by pressure on the median nerve, as it passes into the hand.

    Cryptic tonsils – Symptoms, Causes, Treatment, Prevention
    Cryptic tonsils, also known as tonsil stones or tonsilloliths, are a medical condition that looks like white beads in your tonsils. The word "cryptic"

    Myrbetriq vs Vesicare – Uses, doses, side effects, differences
    Myrbetriq vs Vesicare - Uses, doses, side effects, differences
    Myrbetriq It is the brand name of a drug called mirabegron. It belongs to a class of medications called beta-3 adrenergic agonists that reduce

    Spotted fever of the Rocky Mountains in the face of Lyme disease – Differences and treatment
    Spotted fever of the Rocky Mountains in the face of Lyme disease - Differences and treatment
    This article reveals the differences between rocky mountain spotted fever and Lyme disease: Rocky Mountain Fever (RMSF) This disease is caused by bacteria that

    Tedizolid vs Linezolid – Uses, side effects, differences
    Tedizolid vs Linezolid - Uses, side effects, differences
    Tedizolid It is a medicine (brand name – Sivextro) that belongs to a class of medications called oxazolidinone antibiotics. This medication is used to

    Top 10 essential oils for kidney stone pain
    Kidney stones are small rocks that develop in the kidney. They form when certain chemicals concentrate enough in the urine to form crystals. Kidney

    Is Flexeril addictive? + Uses, drug interactions, side effects
    It's addictive Flexeril + uses, drug interactions, side effects
    Flexeril is the brand name of a medication called cyclobenzaprine that is part of a class of medications called skeletal muscle relaxants. This medication


    Leave a Reply

    Your email address will not be published. Required fields are marked *