A clinical study confirms the effect of the furocisto on PCOS
Fenugreek seed extract (Furocisto) causes a significant reduction in the volume of the ovary and a reduction in the size of the cyst. A clinical study conducted on 50 women in the age group of 18-45 showed significant results in the Treatment of polycystic ovary syndrome. Patients with the use of fenugreek seed extract (furocisto). Average IMC of the studied population was 23.88 and had adequate hepatic, renal and hematological functions. At the time of enrollment, most patients had a prolonged menstrual cycle (81%) and some had an irregular cycle (10%). The rest of the patients (10%) had primary infertility.
Effect of furocisto on PCOS in pregnancy
It is observed that women who have PCOS have problems to conceive. During the study, a significant percentage (12%) of the study population became pregnant during the treatment of PCOS with Fenugreek Seed Extract (Furocyst). Three pregnancies were observed after 30 days, one each after 70 days, 84 days and 39 days of treatment.
Effect of the furocisto in the SOP in the volume of the ovary
Compared to the reference data, subjects showed a significant reduction in ovarian volume at the end of the study. The volume of the left ovary was reduced by 17.82% and the volume of the right ovary was reduced by 28.25%.
Effect of the furocisto in the SOP on the cysts.
The enrolled subjects showed reduction in the size of the cyst. Of the total of 50 subjects, 46% of the subjects showed a reduction in the size of the cyst and 36% of the subjects showed a complete dissolution of the cysts at the end of the study. A total of 6 patients became pregnant during the study. The general percentage of the study population that responds positively to the fenugreek extract is 94%.
Effect of the furocisto in the menstrual cycle
There was a significant improvement in the menstrual cycle with the consumption of fenugreek seed extract. At the end of the last visit, 71% of patients had regular cycles, 19% of patients reported prolonged cycles and appx. 10% reported primary infertility. None of the patients reported an irregular cycle at the end of the fenugreek extract dosing program.
Effect of furocisto on follicle stimulating hormone and Hb
A significant increase in follicle stimulating hormone levels was observed after 8 weeks compared to the reference value (p = 0.010). A significant increase in Hb levels was also observed when completing the fenugreek dosing schedule compared to the reference value (p = .000). The study showed that Furocyst is completely safe. No significant changes were observed in serum liver function, serum renal function and blood count.
Insulin that acts directly on the ovary, alone or together with LH can improve the production of androgens in the ovaries. It can also indirectly increase androgen levels by reducing the hepatic production of SHBG (sex hormone-binding globulin) and IGFBP-1 (insulin-like growth factor binding protein) and, therefore, elevates free testosterone and free IGF-I, IGF-II levels (growth similar to insulin). factor). The excess of androgens impairs folliculogenesis, which results in a menstrual disorder, development of multiple cysts in the ovary. Insulin resistance increases the risk of developing metabolic disorders, such as diabetes, hypertension, dyslipidemia and cardiovascular events in these women.
Furocyst improves insulin sensitivity and, in turn, regulates circulating androgen levels. It improves the elimination of glucose mediated by insulin in women with PCOS. The furocyst improved the menstrual period in the subjects of the study and has a regulating effect of insulin in the ovarian androgen biosynthesis, the proliferation of teak cells and endometrial growth. It regulates the production of ovarian androgens, which leads to the disappearance or reduction of the size and number of cysts. An increase in the proportion of LH (luteinizing hormone) / FSH (follicle stimulating hormone) has been reported in several studies performed in patients with PCOD. Due to the decrease in the level of follicle stimulating hormone (FSH) in relation to LH, ovarian granulosa cells can not aromatize androgens to estrogen, which leads to decreased levels of estrogen and subsequent anovulation . In the present study, a significant decrease in the LH / FSH ratio was observed, suggesting a regulatory effect of the furocyst (fenugreek extract).
Results of the clinical study of the effect of furocyst in PCOS.
The fenugreek seed extract (furocisto) caused a significant reduction in the volume of the ovary. 46% of the population studied showed a reduction in the size of the cyst. 36% of the studied population showed complete dissolution of the cysts. 12% of the patients became pregnant. 71% of patients reported a regular menstrual cycle at the end of treatment. In general, 94% of patients reported positively or benefited from the dose of fenugreek extract.
Furocyst is an innovative product (extracted and developed through a novel and innovative process patented by the USA) that involves the separation of active ingredients from the natural plant without affecting the chemical properties of the active fractions. No chemical products are used. It is a natural dietary supplement and promising effective for the management of polycystic ovary syndrome (PCOS).
Effect of furocisto in PCOS (polycystic ovarian syndrome).