It is the generic name of a medication that is part of a class of medications called antihistamines. It can be found under the following brand names: Aller-Chlor, Chlo-Amine, PediaTan, Triaminic Allergy or Ed ChlorPed.
Mechanism of action
It works by blocking the action of histamine in the body.
This medication is used to relieve the symptoms of sinus congestion, runny nose, sinus pressure, watery eyes, itchy throat and nose, and sneezing due to hay fever, upper respiratory infections, and allergies.
For sustained release, the usual recommended dose is 8 to 16 mg orally every 8 to 12 hours, as needed. For tablets, the usual recommended dose is 4 mg orally every 4 to 6 hours.
Notes: Talk to your health care provider if your symptoms do not improve after 7 days of treatment. Do not take this medication for more than 7 days in a row.
Side effects and precautions
Common side effects may include:
blurry vision; drowsiness; feeling nervous or restless; constipation; dry mouth or throat; dizziness.
Rare side effects may include:
feeling short of breath; uneven heart rate; little or no change of mood when urinating; unusual weakness; seizures (convulsions); bruising easily; tremor.
Note – Contact dermatitis (a condition that reddens or inflames the skin) has been attributed to chlorphenamine in combination with other compounds.
Before taking this antihistamine, tell your healthcare provider if you have:
if you are having an asthma attack; Narrow-angle glaucoma; if you can not urinate; an enlarged prostate; A blockage in your intestines.
Avoid consuming alcoholic beverages while taking this antihistamine, since alcohol consumption can substantially increase the risk of side effects.
You may interact negatively with other medications, especially:
hydrocodone; cetirizine; Xanax (alprazolam); Cymbalta (duloxetine); Zyrtec (cetirizine); dextromethorphan; sertraline Lyrica (pregabalin); Norco (acetaminophen / hydrocodone).
Pregnancy and lactation
This antihistamine can pass into breast milk and cause harm to the baby. In addition, it can slow the production of breast milk. Do not use this medicine without the advice of your healthcare provider if you are breast-feeding a baby.
It is not expected that this antihistamine will harm a developing fetus. Do not use this medicine without the advice of your medical professional if you are pregnant.
It's the brand of a medicine called diphenhydramine, which is part of a family of medications called antihistamines.
Before using this antihistamine, tell your healthcare professional if you have:
an allergy to diphenhydramine; an enlarged prostate; kidney disease; an overactive thyroid; a colostomy or ileostomy; increased pressure in the eye; a stomach ulcer glaucoma; liver disease; a cough caused by emphysema; chronic obstructive pulmonary disease; obstruction in your digestive tract; asthma; heart disease; obstruction of the bladder; low blood pressure.
Mechanism of action
This medication works by blocking the effects of a natural compound that is released by the body, called histamine.
Diphenhydramine It is related to ethanolamine and has antiemetic, antickinetic, anticholinergic, antiviral, sedative and local anesthetic properties.
Do not drink alcohol while using this antihistamine since alcohol may increase the risk of side effects.
This medication is used to treat runny nose, sneezing, rash, hives, itching, watery eyes, and other symptoms of seasonal or year-round allergies.
In addition, this medication is used to induce sleep, to suppress cough, to treat dizziness, and to treat mild forms of Parkinson's disease.
Important note – It is not recommended to administer this medicine to children under 6 years of age.
The usual recommended dose is 25-50 mg every 4-6 hours. The maximum recommended dose should not exceed 400 mg per day.
This antihistamine can interact with:
antidepressants; prednisolone acetate; allergy medications; monoamine oxidase inhibitors; any other drug that makes you feel sleepy or relaxed; potassium supplements, including – Polycitra; over-the-counter cold medicines; Anxiety or sleeping drugs.
Pregnancy and lactation
It can pass into breast milk and adversely affect the breast-fed baby, therefore, avoid antihistamine if you are breast-feeding a baby.
There are no studies on the safe use of this antihistamine during pregnancy, therefore, contact your health care Professional before using this antihistamine if you are pregnant.
Side effects It can include:
enlarged prostate; drowsiness; constipation headaches; dry mouth; nausea; double vision; Stomach ache; loss of appetite; disturbed coordination; dizziness; fatigue; blurry vision; Difficulty urinating; tremor; fatigue.
Note – diphenhydramine Overdose can cause central nervous system and cardiovascular effects. In addition, the misuse of this medication seems to be associated with an increase in energy, a high mood and, in some cases, hallucinogenic effects.
Final result: chlorpheniramine versus diphenhydramine (Benadryl)
Chlorpheniramine (brand names: Aller-Chlor, Chlo-Amine, PediaTan, Triaminic Allergy, or Ed ChlorPed) is an antihistamine that is used to treat sneezing, itching, runny nose, and watery eyes caused by a cold common, allergies or flu. It works by reducing the effects of histamine in the body. It is a first generation antihistamine medication.
Benadryl (active ingredient – diphenhydramine) is a medication that is effective in treating the symptoms of mild allergy and common cold, as well as sneezing, hives, runny nose and itching. Diphenhydramine is a first generation antihistamine drug.
Regarding its price, the average retail price of 100 tablets of chlorpheniramine 4 mg is $ 9, while the average retail price of 100 capsules of Benadryl 25 mg is $ 18.
Chlorpheniramine versus diphenhydramine (Benadryl) – Comparison of uses and side effects, Source: https://www.yourhealthremedy.com/health-tips/chlorpheniramine-vs-diphenhydramine/
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