Caffeine anhydrous versus caffeine – Benefits, side effects, differences

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Caffeine anhydrous versus caffeine - Benefits, side effects, differences

Caffeine Anhydrous (CA)

It is a pure and powdered version of caffeine, which is normally a crystalline substance. Anhydrous means "without water" or "free of water", therefore, CA means only caffeine without water.

CA belongs to a group of stimulants called xanthines, which naturally occur mainly in coffee, cocoa and tea. It is synthesized by boiling parts of plants (beans, stems and leaves) in water. Once the water evaporates and the parts of the plant are removed, what remains is a dry, white, crystalline powder.



It helps reduce food cravings temporarily. Therefore, you can control hunger and decrease the daily intake of food. In addition, it is involved in the decomposition of fat. This process is known as lipid oxidation (the process in which free radicals steal electrons from fat cells) and has the greatest impact on obese and overweight people.

In addition, its diuretic properties are also an advantage, since excess water can be eliminated from the body by purifying it, since diuresis (increased urine formation by the kidney) also eliminates metabolic waste.


CA is structurally similar to adenosine (a chemical in the body and brain that belongs to a class of substances called neurotransmitters), however, CA increases cellular activity rather than decreasing it.

The inhibition of this neurotransmitter can influence the activity of serotonin, dopamine (a neurotransmitter that helps control the reward and pleasure centers of the brain), adrenaline and acetylcholine. This translates into a higher level of vigil than Increase metabolism and energy levels..


Type 2 Mellitus diabetes is characterized by Elevated levels of blood sugar (glucose) in the context of an inability to secrete insulin or insulin resistance. It is a major health problem, which currently affects more than 335 million people worldwide.

People who increased their caffeine intake over a 4-year period had a 11% lower risk of type 2 diabetes mellitus than those who did not increase their caffeine intake, according to a 2014 study conducted at Harvard.

Athletic performance

Using CA as a supplement before any type of physical exercise can significantly improve results, performance and recovery. This makes it an excellent complement to any pre-workout regime. For marathon runners, perhaps the most important benefit of CA is that it increases the body's use of fat as a source of fuel, therefore it preserves glycogen (a form of storage glucose that is easily mobilized).

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According to a recent study in Spain, athletes who took CA as a supplement burned 15% more calories for 3 hours after physical activity than those who received a placebo. In addition, CA reduces the perception of muscle pain and pain during moderate to intense physical exercise. This means that you can practice the exercise for longer without feeling exhausted or broken in the middle of the session.

The amount of caffeine that is required to see its effects of increased performance is in the range of 3 to 6 mg per kilogram of body mass.

Liver health

Chronic liver diseases They are frequent causes of death related to the disease in the United States and throughout the world. For example, in the USA. UU., More than 31,000 people die each year from cirrhosis (progressive, chronic liver scarring).

Caffeine can reduce fatty liver in people with fatty liver disease not related to alcohol, according to a study conducted at Duke University. In addition, when taken as a caffeine enema, it cleanses the colon and detoxifies the liver. More importantly, observational studies have concluded that it may have beneficial effects for patients with hepatocellular cancer (a primary malignant neoplasm of the liver).

Parkinson's disease

It has been shown that reduce the risk to develop Parkinson's disease (Symptoms include tremors, muscle stiffness and changes in speech), and can be used to reduce some of the motor problems associated with this neurodegenerative disorder.

Side effects

Interacts with any prescription or over the counter medications, such as – depression and psychiatric drugs, thyroid medications, medicine for stomach acid Tagamet (Cimetidine), and the antibiotic Cipro.

Excessive intake of CA can cause calcium to be eliminated from the body through urine. In addition, it impacts the absorption of calcium, which ultimately leads to weaker bones and osteoporosis.

It can also alter sleep patterns and increase anxiety, leading to an unhealthy cycle of restless sleep, relying on this stimulant to help with daytime sleepiness.

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Note – More than 85% of American adults ingest this stimulant every day (one way or another), and scientists established that many people who are heavily dependent on this stimulant experience withdrawal symptoms. Interestingly (and worryingly), the scientists reported that these people would not stop taking caffeine even if it put them at higher risk of cardiovascular disease or during pregnancy.


It is the most consumed psychoactive compound in the United States and throughout the world. It has a structure similar to xanthine, theobromine and theophylline. Its stimulant effects can begin as early as 15 minutes after ingestion and can last up to 6 hours, according to the Health Service of the University of Michigan.

It is estimated that the average daily intake is as high as 4 mg / kg of body weight in American adults. This compound is most often consumed in the form of coffee, tea, soft drinks, sports drinks and energy drinks.

The Food and Drug Administration recommends a maximum intake of 400 mg per day. Pregnant and breastfeeding women should avoid taking too much of this stimulant. According to studies, an intake of 300 mg or more per day could contribute to spontaneous abortion. In addition, some experts recommend limiting your intake to less than 150 mg per day during pregnancy.

Caffeine anhydrous vs caffeine – Differences

CA is a potent form of caffeine supplied as a white crystalline powder. Normally it is used as:

supplements to lose weight; accelerating energy supplements; analgesic medications; stay awake pills

In conclusion, the only difference between CA and caffeine is that CA does not have water. In addition, the use of CA in pills is more efficient than the caffeine obtained from coffee because there are variations in the caffeine content in different Cups of coffee, depending on how the beans were roasted and the quality of the coffee grains.


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