Biktarvy is the brand name for a combination of drugs called bictegravir, emtricitabine and tenofovir alafenamide.
Tenofovir alafenamide and emtricitabine are two medications that are considered the "backbone" of anti-HIV treatments. Bictegravir is an inhibitor of the transfer of chains of non-potent integrase (INSTI).
Integrase inhibitors block integrase: an HIV enzyme (an enzyme is a protein that increases speed or initiates a chemical reaction). By blocking this enzyme, this drug can reduce the amount of HIV in the body by preventing HIV from multiplying.
Integrase inhibitor medications are often among the first anti-HIV drugs used in patients who have recently contracted HIV, as they function efficiently and have minimal side effects in the human body.
This type of medication (integrase inhibitors) has made HIV / AIDS a death sentence into a manageable condition. However, patients must remain in life-long treatmentTherefore, there is a growing focus on the manufacture of drugs with few side effects as much as possible.
This medication is produced by Gilead Sciences, Inc. and was approved for the first time by the US Food and Drug Administration. UU For the treatment of HIV-1 infection on February 7, 2018.
the treatment combines three medications (bictegravir, emtricitabine and tenofovir alafenamide) in a daily pill to treat human immunodeficiency virus (HIV) infection in adults.
HIV is a virus that affects the immune system, specifically CD4 cells. These cells help to protect the human body from the disease. Since the first human was infected with HIV, HIV / AIDS has claimed the lives of approximately 35 million people. In addition, at present, more than 35 million people are infected.
HIV is transmitted from person to person through contact with semen and / or vaginal fluid, infected blood and the use of syringes, needles or infected drug equipment.
Symptoms of HIV
According to statistics, 80 percent of people infected with HIV experience a flu-like illness. The symptoms usually last 14 days, but can last even longer. They are a real sign that the immune system is fighting against the HIV virus.
The most common symptoms It can include:
After the early stage of HIV infection, the virus moves to the stage of clinical latency. This can be called chronic HIV infection. In this stage, the virus is active, but it reproduces at much lower rates in the body.
During chronic HIV infection, an infected person may not have any symptoms. For example, some people who do not take any anti-HIV drugs can stay in this phase for a decade or more. However, other patients can pass this stage much faster.
The problem is that if you have this infection and do not have HIV. medicinesOver time, HIV will weaken the immune system of the human body and the patient will progress to acquired immunodeficiency syndrome (AIDS), the late stage of HIV infection. During this stage, patients may experience symptoms such as:
depression; rapid weight loss; memory loss; pneumonia; Neurological disorders; Brown, red or pink spots inside the nose, mouth or eyelids or under the skin; sores in the anus, mouth or genitals; diarrhea that lasts more than seven days; prolonged swelling of the lymph nodes in the groin, armpits, or neck; unexplained and extreme tiredness; Deep night sweats.
Each tablet contains 25 mg of tenofovir alafenamide, 50 mg of bictegravir and 200 mg of emtricitabine.
This medication is a complete pill, a medication regimen that is taken once a day and can be taken without or with food. Therefore, the usual recommended dose for an adult is 1 tablet once a day.
Side effects and precautions of Biktarvy
Because this medication is usually given in combination regimens, it is difficult to determine the exact side effects that are associated with a specific medication within that class. However, the most common side effects may include:
fatigue; Diarrhea; insomnia; nausea headaches.
Rare side effects may include:
changes in liver tests; abnormal dreams; depression; fatigue; dizziness; spinning sensation (vertigo); allergic reactions; changes in the immune system; Changes in body fat.
Before taking this medication, tell your doctor if:
have some other medical condition; have had liver problems, such as – hepatitis B or C infection; Have a kidney disease Have you ever had an allergic reaction to some type of medicine?
Since there are no conclusive clinical studies on the safe use of this medicine during pregnancy or if it will harm the unborn baby, tell your doctor if you are pregnant or plan to become pregnant before using this medicine. Also, do not breast-feed if you take this medicine because if you have HIV-1, the risk of transmitting HIV-1 to your baby is very high. Talk to your doctor about the best method to feed your baby.
Combining any type of medication with alcohol can be dangerous to your health since alcohol can increase the risk of side effects and can interfere with some medications, making them less effective.
If you experience an overdose, call your local poison center, which can be contacted directly by calling the Poison Help toll-free hotline (1-800-222-1222) or your local emergency number.
This medication may interact negatively with other medications, including:
sucralfate ulcer medication (Carafate); rifampicin, an antibiotic used to treat some types of bacterial infections, such as leprosy, tuberculosis and Legionnaires' disease; oral diabetes medication containing metformin (the first-line medication for the treatment of type 2 diabetes mellitus); atazanavir, an antiretroviral drug that is used to treat and prevent HIV / AIDS. Other medicines for HIV or AIDS, such as etravirine, efavirenz, nevirapine, or fosamprenavir / ritonavir; medicine buffered laxatives or antacids that contain magnesium, calcium or aluminum, such as Di-Gel Maalox, Amphojel, Mylanta, Milk of Magnesia, Rolaids, Pepcid Complete, Tums or Rulox; Grass of San Juan; supplements that contain calcium or iron; Medications for seizures, which include: oxcarbazepine, carbamazepine, phenytoin, and phenobarbital. Referenceshttp://www.gilead.com/news/press-releases/2018/2/us-food-and-drug-administration-http://www.telegraph.co.uk/business/2018/02/08/gsk-sues-us-rival-alleged-hivhttps://www.reuters.com/article/brief-gilead-sciences-says-fda-approves/brief
Biktarvy – Uses, side effects, dosage, alcohol, overdose, pregnancy, Source: https://www.yourhealthremedy.com/health-tips/biktarvy/
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