All about platelet-rich plasma

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Blood plasma enriched with platelets is known as Platelet rich plasma (PRP) Being a rich source of similar platelets, PRP can perform tissue and bone healing through the use of various cytokines and growth factors. Platelet plasma therapy is a recognized procedure and is widely used in other methods such as orthopedics, dentistry and dermatology. The indications in dermatology that require PRP are wound healing, androgenetic alopecia, facial rejuvenation, etc. Several protocols are used for the preparation of PRP and, although there is no fixed procedure, the main methods include the collection of platelets in groups, which are 3 to 5 times greater. That the physiological quality. This is followed by the infusion of this concentrated plasma into the tissue where recovery is needed.

PRP is used in tissue repair due to the growth factors present and its efficiency to cure various injuries. Calcium chloride and thrombin They are used to activate the platelets that are collected in the PRP. PRP contains cytokines and growth factors that include:

Keratinocyte growth factor Fibroblast growth factor Insulin-like growth factor 1 Insulin-like growth factor 2 Growth factor derived from platelets Epidermal growth factor Transforming growth factor


The effectiveness of PRP is being evaluated through research. Effectiveness is influenced by factors such as

Body area treated If the disease is chronic or acute Patient's health

There are two standard methods of PRP preparation. In both processes, the patient's blood (anticoagulated using citrate dextrose) is collected and passed through two centrifugation processes, which are designed to separate the concentrated PRP from red blood cells and platelets deficient in plasma. PRP production varies according to different techniques and equipment.

Clinical applications:
In humans, PRP has been used to treat different types of diseases such as androgenic alopecia, osteoarthritisnerve injury plantar fasciitis and chronic tendinitis. It is also used in plastic and Oral surgery as well as for bone repair. After 6 weeks of therapy, patients are advised to rest. 6-12 weeks later, they are checked again to improve. In some cases, there may be a requirement for more than one injection. Most patients report that they can return to normal activities within 3 months.

All about platelet-rich plasma, written by Dr. P. Sharat Kumar at

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