A single course of antibiotics can affect your gut microbiome for one year!

Filed in: Article, gut-health, health-hazards, health-tips.

You lose more than your cold and flu symptoms when you take antibiotics!

In a battle against an infection, antibiotics can bring victory over enemy germs. However, that winning aid of war can come with significant collateral damage; The microbial allies and the innocent are also killed. These casualties may be unavoidable in some cases, but many people take antibiotics when they are not necessary or appropriate. And the number of antibiotics in a healthy microbiome can, in some places, be serious, a new study suggests.

In two randomized, placebo-controlled trials of healthy people, a single course of Antibiotics altered the composition and diversity of the intestinal microbiome. For months, and in some cases up to a year. These changes could clear the way for pathogens, including the deadly Clostridium difficile. These changes in the community can also alter microbial activities, such as interacting with the immune system and helping with digestion. Overall, the data, published on Tuesday in the mBio journal, suggest that antibiotics may have more side effects than previously thought, at least in the gut.

In the mouth, on the other hand, the researchers found that the microbial communities performed much better and recovered weeks after the antibiotic treatments. The finding raises the question of why the oral microbiome is less disturbed by drugs. It could simply be due to the way in which antibiotics, taken orally, circulate throughout the body. Or, it could imply that oral microbiomes are innately more resistant, a quality that would be useful for replicating in microbial communities throughout the body.

Read Also  Emotional stress: how chronic emotional stress can ruin your health

the joint judgments, led by Egija Zaura at the University of Amsterdam, followed 66 healthy participants, 29 in Sweden and 37 in the United Kingdom. At each location, the participants were randomized into a placebo group or into one of the two groups that received antibiotics. The two antibiotics administered in the Swedish trial were an lincosamide (clindamycin) and a quinolone (ciprofloxacin). The UK trial included a tetracycline (minocycline) and a penicillin (amoxicillin).

The researchers sequenced the germs in each person's saliva and feces before and immediately after taking a medication cycle. Then, the researchers conducted a follow-up sampling at 1, 2, 4 and 12 months.

The intestinal microbial diversity was significantly altered by the four types of antibiotics, which lasted for months. In the participants who took ciprofloxacin, the microbial diversity was modified up to 12 months. Antibiotic treatments also caused an increase in the genes associated with antibiotic resistance. Finally, the researchers observed that clindamycin eliminated the microbes that produce butyrate, a short-chain fatty acid that inhibits inflammation, carcinogenesis and oxidative stress in the intestine.

The oral microbiome saw some changes in the community. But the communities surprisingly recovered in a short time, in some cases a week, the authors report. And, the amount of genes associated with antibiotic resistance was generally stable before and after drug treatments.

The authors speculate that the stability of the oral microbiome may be related to the constant onslaught of disorders, such as tooth brushing and changes in humidity and air.

Source: https://www.foodmatters.com/article/a-single-course-of-antibiotics-can-affect-your-gut-microbiome-for-a-year

Tags: intestinal health, health risks, Health Tips

Comments are closed here.

Read Also  How to determine if your liver is toxic when looking at your face
You May Also Like:
How to naturally strengthen your bones
For many, bone density is a concern, almost 1 million Australians, to be exact, and the persistent diagnosis of osteoporosis is a name none

7 tips for a healthy Thanksgiving
When it comes to Christmas celebrations, it can be hard to resist all those extra treats and temptations, with good intentions that sometimes fly

16 Health benefits of drinking hot lemon water
The lemons are vitamin C Rich citrus fruits that enhance their beauty, rejuvenating the skin from the inside, giving a shine to your face.

Be receptive
A new study funded in part by the Agricultural Research Service (ARS) suggests that an alkalizing diet may be an important key to reducing

Funny Friday: What if the animals were obese? (Part 2)
Do you want to see a movie that changes your way of thinking and shows you the power behind your existence? Starting 2015 with

Vitamin B3 to lower cholesterol safely – does it work?
There is a safe, inexpensive, non-prescription, convenient and effective way to reduce high cholesterol levels and reduce the risk of heart disease: niacin. Niacin

25 things you never knew you could do with apple cider vinegar
When I started using apple cider vinegar when I made the Food Matters movie, I was absolutely impressed by its incredible health benefits, and

Does cutting gluten really make you feel better?
Many people can benefit from going gluten-free. Those with celiac disease, gluten sensitivity or autoimmune conditions get the most benefits, but what about all

The tax on sodas that aims to boost education and reduce poverty
With a clinical background in nutrition and professional experience as a dietitian, McKel Hill also knows first hand what it feels like to live

Insomnia, how to sleep naturally
The diet and lifestyle of modern people is the perfect recipe for sleepless nights. Our minds are in constant movement while our bodies feel

Leave a Reply

Your email address will not be published. Required fields are marked *