Good news: CCMB scientists discover a new and promising way to cure muscular dystrophy.
According to the joint study of InBody and Ipsos, 71 percent of Indians suffer from poor muscle health and should gain muscle mass. Bad muscle mass can cause many health problems: deterioration of muscle function, fatigue and poor metabolic health. The study was conducted in eight cities: Delhi-NCR, Mumbai, Calcutta, Chennai, Ahmedabad, Lucknow, Patna and Hyderabad, in people who belonged to the age group of 30 to 55 years.
Many people suffer from different muscular disorders and one of the most feared diseases is muscular dystrophy.
Muscular dystrophy is rare and has no cure. However, there is new hope for patients who suffer from it. Yes, you heard right! In the near future, those affected by this deadly disease can wait to be cured
After a 6-year study, scientists at the Center for Cellular and Molecular Biology of the Council for Scientific and Industrial Research (CSIR) discovered a pathway that will now pave the way for advanced studies in mice, to understand whether drugs can be developed to those who suffer from the disease. On July 24, the research was published in the journal Science Signaling.
Muscular dystrophy can be called a group of inherited diseases that can damage and weaken muscles due to the lack of a protein called dystrophin (necessary for normal muscle function). There are more than 30 types of muscular dystrophy: duchenne, becker, congenital, etc. But now patients with muscular dystrophy can breathe a sigh of relief! The director of CCMB, Rakesh Mishra, said that a drug can be developed to ensure that the cells enter sleep mode so that they are ready for regeneration and can help in specialized treatment. Therefore, the findings of this study have discovered an important phenomenon in biology. Now, there is new hope for patients suffering from muscle diseases that drug therapy may be possible in the future.
When the research was done on mice, the stem cells woke up during the injury and worked for muscle regeneration. This discovery by Dr. Jyotsna Dhawan, chief scientist of CCMB, together with Ajoy Aloysius is a milestone in the field of medicine.
According to Dr. Dhawan, the body's mechanism is in place to repair the damage while the dormant cells were awake. Due to the constant workload, the stem cells are depleted or require external intervention in which they can work to repair themselves if one is dystrophic. The process requires greater understanding and additional research is also needed.
According to Aloysius, to improve the stock of stem cells in diseased muscles, new therapeutic strategies can be devised due to the research findings. He also said that there can be muscle regeneration and reduction of muscular waste if this line of research is followed.
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Reference: https://www.thehealthsite.com/news/a-new-hope-for-muscular-dystrophy-patients-av0718/, by Aishwarya Vaidya